34981-38-9

Usage

Uses

Used in Organic Synthesis:
4-chlorotoluene-2-sulphonyl chloride is used as a key intermediate for the synthesis of various organic compounds. Its reactivity allows for the formation of new chemical bonds and the creation of a wide range of products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-chlorotoluene-2-sulphonyl chloride is used as a building block for the development of new drugs. Its unique chemical structure makes it a valuable component in the design and synthesis of pharmaceutical compounds.
Used in Agrochemicals:
4-chlorotoluene-2-sulphonyl chloride is also utilized in the agrochemical industry for the production of various agrochemical products. Its role in this industry is to contribute to the development of effective and safe chemicals for agricultural applications.
Used in Dyestuff Industry:
In the dyestuff industry, 4-chlorotoluene-2-sulphonyl chloride is employed as an intermediate for the synthesis of various dyes and pigments. Its chemical properties make it suitable for the production of a range of colorants used in different applications.

InChI:InChI=1/C7H6Cl2O2S/c1-5-2-3-6(8)4-7(5)12(9,10)11/h2-4H,1H3

Upstream product

• 106-43-4 para-chlorotoluene 
• 95-79-4 5-chloro-2-methyl-benzenamine 

Downstream Products

• 18858-06-5 5-chloro-2-methylthiophenol 
• 51896-26-5 2-aminosulfonyl-4-chlorotoluene 
• 46149-10-4 6-chloro-1,2-benzisothiazol-3(2H)-one 1,1-dioxide 
• 26638-53-9 8-chloro-10,10-dioxo-11-methyl-5,11-dihydrodibenzo<1,2>thiazepin-5-one 
• 1353889-40-3 5-chloro-N'-((5-cyanopyrazolo[1,5-a]pyridin-3-yl)methylene)-N,2-dimethylbenzenesulfonohydrazide 
• 80568-07-6 ethyl 2-<(5-chloro-2-methylphenyl)thio>-5-nitrobenzoate 
• 874514-66-6 2-(5-chloro-2-methyl-phenylsulfanyl)-4-methyl-benzoic acid 
• 408351-36-0 2-(5-chloro-2-methyl-phenylsulfanyl)-benzoic acid 
• 479-50-5 lucanthone 
• 57450-55-2 1-chloro-4-methyl-9H-thioxanthen-9-one 

Relevant academic research and scientific papers

Quinazolinone Compound and Application Thereof

The present invention relates to a series of quinazolinone compounds and applications thereof as PI3Kα inhibitors. In particular, the present invention relates to a compound shown in formula (I) and a tautomer or pharmaceutically acceptable salt thereof.

Preparation method of intermediate for preparing tianeptine sodium

The invention discloses a preparation method of an intermediate compound for preparing tianeptine sodium. The intermediate compound is shown as a formula. According to the synthesis method, p-chlorotoluene is used as a starting raw material to react with chlorosulfonic acid to obtain sulfonyl chloride, the sulfonyl chloride undergoes an amidation reaction with N-methylaniline under alkaline conditions to obtain sulfonamide, an aqueous solution of the sulfonamide and air are continuously pumped into a fixed bed reactor loaded with an immobilized catalyst according to a certain ration for oxidation to obtain carboxylic acid, and then the carboxylic acid is subjected to cyclization under catalysis of a solid acid to obtain the target compound. The method has simple and few steps, the cost ofthe raw materials is low, the fixed bed reactor and the solid acid catalyst are utilized, the catalyst can be repeatedly recycled to reduce the discharge of the three wastes, the production process isenvironmentally friendly, and the method is more suitable for industrial production.

Some new 1,2-benzothiazine derivatives with analgesic and anti-inflammatory activities

Twenty-three new 7-halo-4-hydroxy-2H(or alkyl)-N-(3-aralkyl-2-thio-l-hydantoinyl)-2H- 1,2-benzothiazine-3-carboxamide 1,1-dioxide derivatives were synthesized through the condensation of 7-halo-4-hydroxy-2H(or alkyl)-1,2-benzothiazine-3-carboxylic acid methyl ester 1,1-dioxides with 1-amino-2-thio-3-aralkyl-imidazolidine-4-one. The analgesic and anti-inflammatory activities of the synthesized compounds were investigated by acetic acid-induced writhing syndrome and carrageenan rat paw edema tests. In analgesic activities most compounds exhibited higher activities than acetylsalicylic acid, but in antiinflammatory activities most compounds except compounds 24, 36, 39 showed lower activities than indometacin.

Herbicidal sulfonamides

4-Chloro-2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)aminocarbonyl]aminosulfonyl]benzoic acid (1-methylethyl) ester has unexpectedly been discovered to be an outstanding agricultural chemical. The compound is a highly active preemergent and/or postemergent herbicide. The invention includes the compound, compositions containing the compound, and its method-of-use as an agricultural chemical.