34983-48-7 Usage
Uses
Used in Biological Research:
2-(METHYLTHIO)-ADENOSINE 5'-TRIHYDROGEN DIPHOSPHATE TRISODIUM is used as a research tool for studying the activation of P2Y1, P2Y12, and P2Y13 receptors. Its application is particularly relevant in the investigation of purinergic ATP signal transduction, which is mediated through calcium flux in various cell types.
Used in Podocyte Research:
In the specific context of podocyte cells isolated from rat glomerulus, 2-(METHYLTHIO)-ADENOSINE 5'-TRIHYDROGEN DIPHOSPHATE TRISODIUM is used as a biochemical agent to promote the study of P2Y1, P2Y12, and P2Y13 protein activation. This is important for understanding the role of these receptors in podocyte function and their potential involvement in kidney-related diseases.
Biological Activity
Potent purinergic agonist displaying selectivity for P2Y 1 , P2Y 12 and P2Y 13 receptors (pEC 50 = 8.29 and 9.05 for P2Y 1 and P2Y 12 , EC 50 = 19 nM for P2Y 13 ). Induces aggregation of, and inhibits cAMP accumulation in, platelets in vitro .
Check Digit Verification of cas no
The CAS Registry Mumber 34983-48-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,9,8 and 3 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 34983-48:
(7*3)+(6*4)+(5*9)+(4*8)+(3*3)+(2*4)+(1*8)=147
147 % 10 = 7
So 34983-48-7 is a valid CAS Registry Number.
InChI:InChI=1/C11H17N5O10P2S/c1-29-11-14-8(12)5-9(15-11)16(3-13-5)10-7(18)6(17)4(25-10)2-24-28(22,23)26-27(19,20)21/h3-4,6-7,10,17-18H,2H2,1H3,(H,22,23)(H2,12,14,15)(H2,19,20,21)/t4-,6-,7-,10-/m1/s1
