350031-26-4

Upstream product

• 96-09-3 styrene oxide 
• 540-63-6 ethane-1,2-dithiol 

Downstream Products

• 24890-52-6 1-phenyl-1-(2,4-dimethoxyphenyl)ethylene 
• 91875-38-6 2-(2-[(2-oxo-2-phenylethyl)sulfanyl]ethylsulfanyl)-1-phenyl-1-ethanone 

Relevant academic research and scientific papers

The green method for regiospecific ring opening of epoxide with dimercaptoethane

A simple, efficient, and environmentally friendly one-step regiospecefic ring opening of strained epoxides with dimercaptoethane as a nucleophile in nearly saturated aqueous potassium carbonate is reported. The synthesized ,'-dihydroxydithioether compound

Synthesis and biological evaluation of some new thioether-ester crown ethers

New thioether-ester crown ethers have been synthesized starting from oxalyl chloride and different β,β′-dihydroxydithioethers. The synthesized compounds are screened for their antibacterial activity. Among the macrocyclic thioether-esters (5a-j), only 5,12-di[(allyloxy)methyl]-1,4-dioxa-7, 10-dithiacyclododecane-2,3-dione (5e) and 5,12-di(isopropoxymethyl)-1,4-dioxa-7, 10-dithiacyclododecane-2,3-dione (5f) were effective inhibitors against Staphilococcus aureus methicillin resistance and Pseudomanas aeruginosa with an MIC value of 525 and 265 μM. Structures of the synthesized compounds have been confirmed by 1H NMR, 13C NMR, and MS spectral studies. Copyright Taylor & Francis Group, LLC.

Dimercaptoethane oxirane ring opening reaction: β,β′-dihydroxy dithioether synthesis

The action of dimercaptoethane on alkyl oxiranes in the presence of benzyltrimethylammonium hydroxide (Triton B) allows, via regiospecific opening reaction, the preparation of the corresponding β,β′-dihydroxy dithioethers in excellent yields.

Synthesis of new symmetric disubstituted dithioether dithiols

The β, β'-dihydroxydithioethers, derived from oxirane, have been converted into dithioethers dithiols in good yields. A colloidal solution of gold nanoparticles (AuNPs) with 5,8-dithiadodecane-3,10-dithiol was prepared and showed a good stability from tight binding offered by the thiol group on the Au surfaces. Copyright

Synthesis of new β,β'-diketodithioethers via swern oxidation and study of their hydrazone formation rate

The synthesis of β,β'-diketodithioethers 4b-j from corresponding β,β'-dihydroxydithioethers 3b-j was carried out by a Swern oxidation using DMSO-oxalyl chloride as oxidizing agent. β,β'- Dihydroxydithioethers 3b-j were prepared by the reaction of two molar equivalents of epoxides 1b-j with dimercaptoethane 2 in the presence of a saturated aqueous solution of potassium carbonate. The reactivity behavior of imine formation of the β,β'-diketodithioethers 4b-j by 2,4-dinitrophenylhydrazine was also investigated, and a mechanism was proposed by using molecular orbital (MO) calculations. To confirm the proposed mechanism, the role of the thia function to activate hydrazone formation by measuring HOMO-LUMO energy levels was also demonstrated.