350035-36-8Relevant academic research and scientific papers
New aziridine sulfide ligands for palladium-catalyzed asymmetric allylic alkylation
Braga, Antonio L.,Paix?o, Marcio W.,Milani, Priscila,Silveira, Claudio C.,Rodrigues, Oscar E. D.,Alves, Elenilson F.
, p. 1297 - 1299 (2007/10/03)
Aziridine sulfides, a new type of chiral S,N-ligand, have been easily synthesized in a straightforward synthetic route, from an inexpensive and easily available chiral pool. They were used in the Pd-catalyzed asymmetric allylic alkylation of 1,3-diphenyl-2-propenyl acetate with dimethymalonate anion, furnishing the alkylated product in excellent yields and stereo selectivity up to 99%.
New C2-symmetric chiral disulfide ligands derived from (R)-cysteine
Braga, Antonio L,Appelt, Helmoz R,Schneider, Paulo H,Rodrigues, Oscar E.D,Silveira, Claudio C,Wessjohann, Ludger A
, p. 3291 - 3295 (2007/10/03)
Several sulfur-containing optically active C2-symmetrical ligands have been synthesized from (R)-cysteine and applied successfully as chiral catalysts in the asymmetric addition of diethylzinc to aldehydes. The resulting secondary alcohols could be obtained in good yields and excellent enantiomeric excess.
