35015-98-6Relevant academic research and scientific papers
Expeditious synthesis of imidazole-and pyrrole-fused benzodiazocines
Mishra, Amita,Batra, Sanjay
experimental part, p. 4832 - 4840 (2010/10/21)
A straightforward strategy for the synthesis of imidazolefused benzodiazocine from 1-(2-nitrophenyl)-1H-imidazole2-carbaldehyde via Morita-Baylls-Hillman reaction followed by reductive intramolecular cyclization is described. Alternatively the Horner-Wads
Structure activity relationships in reactivators of organophosphorus inhibited acetylcholinesterase. VII. 1 Aryl 2 hydroxyiminomethyl 3 methylimidazolium iodides
Franchetti,Grifantini,Martelli,Stein
, p. 18 - 22,21,22 (2007/10/05)
A series of 1 aryl 2 hydroxyiminomethyl 3 methylimidazolium iodides, where the aryl group is either phenyl or substituted phenyl, was prepared and tested for their reactivating potency on phosphorylated acetylcholinesterase (AChE) and for anti AChE activity. The in vitro testing revealed that some of the new compounds are good reactivators. Correlations between their structure and biological activities have been attempted.
