35022-42-5

Basic information

• Product Name: (2-CHLORO-PHENYL)-OXO-ACETONITRILE
• Synonyms: (2-CHLORO-PHENYL)-OXO-ACETONITRILE;2-CHLOROBENZOYL CYANIDE;Benzeneacetonitrile, 2-chloro-α-oxo-;High Purity (2-Chloro-phenyl)-oxo-acetonitrile CAS NO.35022-42-5
• CAS NO: 35022-42-5
• Molecular Formula: C₈H₄ClNO
• Molecular Weight: 165.58
• Mol File: 35022-42-5.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 257.7 °C at 760 mmHg
• Flash Point: 109.6 °C
• Appearance: /
• Density: 1.311 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: (2-CHLORO-PHENYL)-OXO-ACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: (2-CHLORO-PHENYL)-OXO-ACETONITRILE(35022-42-5)
• EPA Substance Registry System: (2-CHLORO-PHENYL)-OXO-ACETONITRILE(35022-42-5)

Safety Data

• Hazardous Substances Data: 35022-42-5(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 43, p. 2280, 1978 DOI: 10.1021/jo00405a042

Upstream product

• 60-29-7 diethyl ether 
• 21742-26-7 (2-chloro-phenyl)-hydroxyimino-acetonitrile 
• 609-65-4 o-chlorobenzoyl chloride 
• 74-90-8 hydrogen cyanide 
• 89-98-5 2-chloro-benzaldehyde 
• 75-05-8 acetonitrile 
• 118-91-2 ortho-chlorobenzoic acid 
• 544-92-3 copper(I) cyanide 
• 2856-63-5 2-Chlorophenylacetonitrile 
• 7677-24-9 trimethylsilyl cyanide 

Downstream Products

• 196952-95-1 1-(2-chlorophenyl)buta-2,3-dien-1-one 
• 50890-83-0 1-methyl-1H-indazole-3-carboxylic acid 
• 7716-36-1 1-phenyl-1H-indazole-3-carboxylic acid 
• 187243-26-1 N-(o-chlorophenyl)hydantoin 
• 316145-39-8 N-(3-cyanophenyl)- 2-chlorobenzamide 
• 34966-49-9 methyl 2-chlorobenzoylformate 
• 118-91-2 ortho-chlorobenzoic acid 
• 1595288-02-0 2-(cyano(dimethylamino)methyl)phenyl 2-chlorobenzoate 
• 252025-49-3 1-(2,4-dichlorobenzyl)-1H-indazole-3-carbaldehyde 
• 920019-58-5 (1-(2,4-dichlorobenzyl)-1H-indazol-3-yl)methanol 

Relevant articles and documents

Novel synthesis method of alpha-carbonyl acid ester

The invention discloses a novel synthesis method of alpha-carbonyl acid ester. The method comprises the following steps: carrying out chlorination reaction on an alpha-methylene-containing nitrile compound and chlorine to obtain dichloronitrile, reacting the dichloronitrile product in a sulfuric acid and water system to obtain formyl cyanide, then acquiring an imino sulfate compound in the same reaction system, and finally performing esterification to obtain the target product. The adopted reaction raw materials are wide in sources and low in price, highly toxic solid sodium cyanide can be prevented from being used in the prior art, the method is environmentally friendly, and the method is easy to operate, mild in condition and easy to industrialize.

Preparation method for D, L-phenylglycine and analogue thereof

The invention provides a preparation method for D, L-phenylglycine and an analogue thereof. According to the method, benzaldehyde, an analogue thereof and hydrocyanic acid are adopted as raw materials and subjected to cyanidation reaction, and then 2-hydroxy-benzyl cyanide or 2-hydroxy-benzyl cyanide analogue (cyanohydrin for short) is generated. Cyanohydrin reacts with carbon dioxide and the aqueous solution of ammonia, and then 5-phenyl-hydantoin and an analogue thereof (hydantoin for short) are generated. hydantoin is successively subjected to steam stripping, alkaline hydrolysis, steam stripping, decolorization, neutralization, crystallization, washing, centrifuging, drying and the like to obtain D, L-phenylglycine and the analogue thereof. Compared with the prior art, the preparation method for D, L-phenylglycine and the analogue thereof can significantly and effectively reduce the pollution, and fewer inorganic salt by-products are generated. Meanwhile, the prepared D, L-phenylglycine and the analogue thereof are high in product yield and high in purity. Counted in benzaldehyde and the analogue thereof, the yield of D, L-phenylglycine and the analogue thereof is larger than or equal to 96%, and the product purity is larger than or equal to 99%. Meanwhile, the process flow is simple and feasible, so that the method is worthy of market popularization and application.

TETRAAZAPORPHYRIN COMPOUND, COLOR CORRECTION FILTER AND EXTERNAL LIGHT CORRECTION FILTER

PROBLEM TO BE SOLVED: To provide a tetraazaporphyrin compound excellent in light resistance, and a color correction filter and an external light correction filter containing the same. SOLUTION: There is provided a tetraazaporphyrin compound which is a mixture of 4 kinds of isomers obtained by heat cyclization reaction of a metal or a metal derivative with a cis body of 1,2-dicyanoethylene compound represented by the following formula (6) (4 molar) in an alcohol solvent the coexistence of an organic basic. In the formula (6), one of two substitutions Z1 and Z2 is a cyclic alkyl group which may have a substituent and the other is an aryl group which may have a substituent. COPYRIGHT: (C)2016,JPOandINPIT