350231-11-7

Upstream product

• 350231-10-6 (1S)-{1-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-vinyl}-6-isopropenyl-3-methyl-cyclohex-2-enol 
• 848122-40-7 tert-butyl((3-iodobut-3-en-1-yl)oxy)diphenylsilane 
• 16750-82-6 (S)-isopiperitenone 

Relevant academic research and scientific papers

Cascading pericyclic reactions: Building complex carbon frameworks for natural product synthesis

Tandem reactions have emerged as powerful strategies to synthesize complex structures, in particular, processes involving pericyclic reactions. This article describes recent advancement by our group in the development of novel tandem pericyclic reactions

Conservation of the planar chiral information in the tandem oxy-Cope/ene reaction

(Chemical Equation Presented) We report the stereoselective synthesis of a Decalin unit using a tandem oxy-Cope/ene reaction. [3,3]-Shift of 1,2-divinylcyclohexenol 18 generates (1E, 3Z, 7E) cyclodecatrien-2-ol 23 which tautomerizes to ketone 21 (Figure 3

Total synthesis of (+)-arteanniun M using the tandem oxy-Cope/ene reaction.

[see reaction]. The first total synthesis of (+)-arteannuin M was accomplished using the tandem oxy-Cope/transannular ene reaction as the key step to construct the bicyclic core of the natural product. The tandem reaction proceeded with high diastereo- an