35040-32-5 Usage
Uses
Used in Scientific Applications:
2,5-dihydroxy-9H-xanthen-9-one is used as a fluorescent dye for various scientific applications, such as staining and visualization of biological samples, due to its unique fluorescent properties.
Used in Medical Applications:
2,5-dihydroxy-9H-xanthen-9-one is used as a counterstain in histology for highlighting cell nuclei and collagen fibers, aiding in the study and diagnosis of various medical conditions.
Used as a pH Indicator:
2,5-dihydroxy-9H-xanthen-9-one is used as a pH indicator, allowing for the measurement and monitoring of acidity or alkalinity in different solutions.
Used in Textile Industry:
2,5-dihydroxy-9H-xanthen-9-one is used as a dye in the textile industry for coloring fabrics, thanks to its vibrant color and staining properties.
Used in Disinfectants and Antiseptics:
2,5-dihydroxy-9H-xanthen-9-one is used as an antimicrobial agent in disinfectants and antiseptics, leveraging its ability to inhibit the growth of microorganisms and promote cleanliness and hygiene.
Check Digit Verification of cas no
The CAS Registry Mumber 35040-32-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,0,4 and 0 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 35040-32:
(7*3)+(6*5)+(5*0)+(4*4)+(3*0)+(2*3)+(1*2)=75
75 % 10 = 5
So 35040-32-5 is a valid CAS Registry Number.
35040-32-5Relevant academic research and scientific papers
Synthesis of xanthone derivatives and studies on the inhibition against cancer cells growth and synergistic combinations of them
Liu, Jie,Zhang, Jianrun,Wang, Huailing,Liu, Zhijun,Zhang, Cao,Jiang, Zhenlei,Chen, Heru
, p. 50 - 61 (2017/04/06)
34 Xanthones were synthesized by microwave assisted technique. Their in?vitro inhibition activities against five cell lines growth were evaluated. The SAR has been thoroughly discussed. 7-Bromo-1,3-dihydroxy-9H-xanthen-9-one (3-1) was confirmed as the most active agent against MDA-MB-231?cell line growth with an IC50 of 0.46?±?0.03?μM. Combination of 3-1 and 5,6-dimethylxanthone-4-acetic acid (DMXAA) showed the best synergistic effect. Apoptosis analysis indicated different contributions of early/late apoptosis and necrosis to cell death for both monomers and the combination. Western Blot implied that the combination regulated p53/MDM2 to a better healthy state. Furthermore, 3-1 and DMXAA arrested more cells on G2/M phase; while the combination arrested more cells on S phase. All the evidences support that the 3-1/DMXAA combination is a better anti-cancer therapy.
