350482-53-0Relevant academic research and scientific papers
Iterative approach to polyketide-type structures: Stereoselective synthesis of 1,3-polyols utilizing the catalytic asymmetric Overman esterification
Binder, Joerg T.,Kirsch, Stefan F.
, p. 4164 - 4166 (2008/03/27)
An iterative systematic approach to the 1,3-polyol motif has been developed to provide access to all possible stereoisomers by utilizing the catalytic asymmetric Overman esterification for the construction of all stereogenic centres. The Royal Society of
Cytotoxic activity of (S)-goniothalamin and analogues against human cancer cells
De Fatima, Angelo,Kohn, Luciana K.,De Carvalho, Joao Ernesto,Pilli, Ronaldo A.
, p. 622 - 631 (2007/10/03)
(R)- and (S)-Goniothalamin (1) and analogues 2-9 were efficiently prepared in high overall yield and enantiomeric purity, and their cytotoxic activities were evaluated against eight human cancer cell lines. A structure-activity relationship study (SAR) al
Asymmetric allylboration for the synthesis of β-hydroxy-δ-lactone unit of statin drug analogs
Reddy, M. Venkat Ram,Brown, Herbert C.,Ramachandran, P. Veeraraghavan
, p. 239 - 243 (2007/10/03)
Acrylic esters of homoallylic alcohols prepared in 92-96% ee via the asymmetric allylboration of appropriate aldehydes with B-allyldiisopinocampheylborane, upon ring-closing metathesis in the presence of 10mol% of Grabbs' catalyst provided the correspondi
