35050-55-6 Usage
Description
Tomaymycin, a natural product derived from Streptomyces sp. RM-4-15, exhibits significant anticancer properties. It is a member of the enediynes class, characterized by its potent cytotoxic and antitumor activities. Tomaymycin inhibits the proliferation of cancer cells by binding to the minor groove of DNA, causing DNA damage and ultimately leading to cell death. Its discovery and characterization have highlighted the potential of natural products as sources for developing new anticancer agents and as valuable tools for studying DNA damage and repair mechanisms.
Uses
Used in Pharmaceutical Industry:
Tomaymycin is used as a potential anticancer agent for its ability to inhibit the proliferation of cancer cells both in vitro and in vivo. Its mechanism of action involves binding to the minor groove of DNA, resulting in DNA damage and cell death.
Used in Cancer Research:
Tomaymycin serves as a valuable tool in cancer research for studying the mechanisms of DNA damage and repair. Its potent cytotoxic and antitumor activities make it a promising candidate for the development of novel anticancer drugs, providing insights into the potential of natural products in cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 35050-55-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,0,5 and 0 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 35050-55:
(7*3)+(6*5)+(5*0)+(4*5)+(3*0)+(2*5)+(1*5)=86
86 % 10 = 6
So 35050-55-6 is a valid CAS Registry Number.
InChI:InChI=1/C16H20N2O4/c1-4-9-5-12-15(22-3)17-11-7-13(19)14(21-2)6-10(11)16(20)18(12)8-9/h4,6-7,12,15,17,19H,5,8H2,1-3H3/b9-4+/t12-,15?/m1/s1
35050-55-6Relevant articles and documents
Process for conversion of oxotomaymycin to tomaymycin
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, (2008/06/13)
A new chemical procedure for conversion of the biologically inactive fermentation product, oxotomaymycin, to the antibiotic, tomaymycin is disclosed as well as novel intermediates employed in such procedure.
