350590-73-7

Basic information

• Product Name: RAT IL-10
• Synonyms: RAT INTERLEUKIN-10;RAT IL-10;RAT CSIF;RAT B-TCGF;RECOMBINANT RAT IL-10;RAT TGIF;INTERLEUKIN-10;INTERLEUKIN-10, RAT
• CAS NO: 350590-73-7
• EINECS: 201-064-4
• Product Categories: monoclonal antibody
• Mol File: 350590-73-7.mol
• Article Data: 0

Chemical Properties

• Appearance: /buffered aqueous glycerol solution
• Storage Temp.: −20°C
• CAS DataBase Reference: RAT IL-10(CAS DataBase Reference)
• NIST Chemistry Reference: RAT IL-10(350590-73-7)
• EPA Substance Registry System: RAT IL-10(350590-73-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 350590-73-7(Hazardous Substances Data)

Usage

Description

RAT IL-10, also known as Interleukin-10, is a cytokine protein derived from rats. It plays a crucial role in regulating the immune system and has anti-inflammatory properties. RAT IL-10 is involved in various biological processes, including the modulation of immune responses and the promotion of tissue repair.
Source:
RAT IL-10 is typically sourced from rat cells or can be produced through recombinant DNA technology.
Production Methods:
RAT IL-10 can be produced using various methods, such as recombinant expression in host cells like Escherichia coli or yeast, or through extraction from rat tissues.

Uses

Used in Immunological Research:
RAT IL-10 is used as a research tool for studying the immune system and its regulation. It helps researchers understand the role of cytokines in immune responses and inflammation.
Used in ELISA Cytokine Assays:
RAT IL-10 is used as a standard in enzyme-linked immunosorbent assay (ELISA) cytokine assays. These assays are essential for quantifying the levels of specific cytokines, such as RAT IL-10, in biological samples, which can be useful in diagnosing and monitoring various immune-related conditions.
Used in Pharmaceutical Development:
RAT IL-10 can be employed in the development of new drugs targeting immune-related disorders. By understanding the role of RAT IL-10 in immune regulation, researchers can design drugs that modulate its activity, potentially leading to novel therapeutics for conditions like autoimmune diseases and chronic inflammation.
Used in Cell Culture and Tissue Engineering:
RAT IL-10 can be used in cell culture and tissue engineering applications to promote cell growth, differentiation, and tissue repair. Its anti-inflammatory properties can be beneficial in creating a favorable environment for cell growth and tissue regeneration.

Biochem/physiol Actions

Interleukin-10 regulates lymphoid and myeloid cell functions. It blocks the activation of cytokine synthesis and several accessory functions of macrophages. IL-10 enhances cytotoxic T cell development and co-stimulates B cell differentiation and Ig secretion. IL-10 regulates angiogenesis by inducing cell-type dependent expression of either angiogenic or angiostatic factors.