350605-32-2

Basic information

• Product Name: 2-(2-iodomethyl)benzyl-2-methylcyclohexane-1,3-dione
• Synonyms: 2-(2-iodomethyl)benzyl-2-methylcyclohexane-1,3-dione
• CAS NO: 350605-32-2
• Molecular Weight: 356.203
• Mol File: 350605-32-2.mol

Chemical Properties

• CAS DataBase Reference: 2-(2-iodomethyl)benzyl-2-methylcyclohexane-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-iodomethyl)benzyl-2-methylcyclohexane-1,3-dione(350605-32-2)
• EPA Substance Registry System: 2-(2-iodomethyl)benzyl-2-methylcyclohexane-1,3-dione(350605-32-2)

Safety Data

• Hazardous Substances Data: 350605-32-2(Hazardous Substances Data)

Upstream product

• 91-13-4 α,α'-dibromo-o-xylene 
• 1193-55-1 2-methylcyclohexane-1,3-dione 
• 474323-68-7 2-(2-bromomethylbenzyl)-2-methylcyclohexane-1,3-dione 

Relevant articles and documents

Sequenced reactions with samarium(II) iodide. Sequential intramolecular Barbier cyclization/Grob fragmentation for the synthesis of medium-sized carbocycles

Samarium(II) iodide was used to access eight-, nine-, and ten-membered carbocycles via a domino reaction composed of a cyclization/fragmentation process. 2-(Iodoalkyl)-, 2-(iodomethyl)allyl-, and 2-(2-iodomethyl)benzyl-2-methyl-3-(methanesulfonyloxy)cycloalkanones were subjected to Barbier-type reductive coupling conditions. Intermediate cycloalkanedione derivatives were also treated under similar conditions, providing bicyclic hydroxy ketones with complete diastereoselectivity and high yields. This method represents a general and efficient approach to a variety of highly functionalized, stereodefined carbocycles.