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2(1H)-Pyrimidinethione, 4-ethyl- (9CI) is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

35071-18-2

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35071-18-2 Usage

Chemical family

Pyrimidinethione

Applications

+ Pharmaceuticals (intermediate in the synthesis of pharmaceuticals)
+ Agrochemicals (intermediate in the synthesis of agrochemicals)
+ Antimicrobial and antifungal properties
+ Materials science (component of polymers, corrosion inhibitor)

Industries

Pharmaceutical, agrochemical, and materials science.

Check Digit Verification of cas no

The CAS Registry Mumber 35071-18-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,0,7 and 1 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 35071-18:
(7*3)+(6*5)+(5*0)+(4*7)+(3*1)+(2*1)+(1*8)=92
92 % 10 = 2
So 35071-18-2 is a valid CAS Registry Number.

35071-18-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-ethyl-2-mercaptopyrimidine

1.2 Other means of identification

Product number -
Other names 4-ethyl-1H-pyrimidine-2-thione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:35071-18-2 SDS

35071-18-2Downstream Products

35071-18-2Relevant academic research and scientific papers

Difluoromethylbenzoxazole pyrimidine thioether derivatives: A novel class of potent non-nucleoside HIV-1 reverse transcriptase inhibitors

Boyer, Jérémie,Arnoult, Eric,Médebielle, Maurice,Guillemont, Jér?me,Unge, Johan,Jochmans, Dirk

experimental part, p. 7974 - 7985 (2012/01/13)

This paper reports the synthesis and antiviral properties of new difluoromethylbenzoxazole (DFMB) pyrimidine thioether derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors. By use of a combination of structural biology study and traditional medicinal chemistry, several members of this novel class were synthesized using a single electron transfer chain process (radical nucleophilic substitution, SRN1) and were found to be potent against wild-type HIV-1 reverse transcriptase, with low cytotoxicity but with moderate activity against drug-resistant strains. The most promising compound 24 showed a significant EC50 value close to 6.4 nM against HIV-1 IIIB, a moderate EC50 value close to 54 μM against an NNRTI resistant double mutant (K103N + Y181C), but an excellent selectivity index >15477 (CC50 > 100 μM).

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