35079-50-6 Usage
Chemical structure
1,4,4-trimethyl-1,2,3,4-tetrahydropyridine
Type of compound
Potent neurotoxin
Association with disease
Linked to the development of Parkinson's disease
Origin
Byproduct of the synthesis of a meperidine analogue
Initial development
Developed as a synthetic opioid analgesic
Side effects
Causes severe and irreversible Parkinson's-like symptoms in users
Legal status
Classified as a Schedule I controlled substance
Mechanism of action
Selectively destroys dopaminergic neurons in the brain, particularly in the substantia nigra
Current use
Primarily used in laboratory settings to induce Parkinson's disease symptoms in animal models for research purposes
Check Digit Verification of cas no
The CAS Registry Mumber 35079-50-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,0,7 and 9 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 35079-50:
(7*3)+(6*5)+(5*0)+(4*7)+(3*9)+(2*5)+(1*0)=116
116 % 10 = 6
So 35079-50-6 is a valid CAS Registry Number.
35079-50-6Relevant articles and documents
Mercuric dehydrogenations of N-tertiary piperidine derivatives with different substitution pattern
Moehrle, H.,Claas, M.
, p. 749 - 753 (2007/10/02)
A comparison of the dehydrogenation of different N-tertiary piperidine derivatives with mercuric EDTA and mercuric acetate shows an increase of the reaction with the complex method.This is especially evident with the N-demethylation of 1,2,2,6,6-pentamethylpiperidine.Generally with dehydrogenations offering a possibility of generating a tertiary or a secondary carbenium ion, the latter alternative is mostly also realized to a minor extent.
