350821-45-3Relevant articles and documents
A general large scale synthesis of 2-alkyl-7-methoxyindoles
Chen, Bang-Chi,Hynes Jr., John,Pandit, Chennagiri R.,Zhao, Rulin,Skoumbourdis, Amanda P.,Wu, Hong,Sundeen, Joseph E.,Leftheris, Katerina
, p. 951 - 960 (2007/10/03)
A general method has been developed for the large scale synthesis of 2-alkyl-7-methoxyindoles and analogs. This method involves an efficient preparation of the key intermediates, 1-(2-nitroaryl)-2-nitroalkanols and 1-(2-nitroaryl)-2-nitroalkenes, and affords 2-alkyl-7-methoxyindoles and analogs in 3 steps with good overall yields.