350998-32-2

Basic information

• Product Name: 5-amino-4-cyano-N-(2-methoxyphenyl)-3-methyl-2-thiophenecarboxamide
• Synonyms: 5-amino-4-cyano-N-(2-methoxyphenyl)-3-methyl-2-thiophenecarboxamide
• CAS NO: 350998-32-2
• Molecular Formula: C14H13N3O2S
• Molecular Weight: 287.33692
• Mol File: 350998-32-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-amino-4-cyano-N-(2-methoxyphenyl)-3-methyl-2-thiophenecarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-amino-4-cyano-N-(2-methoxyphenyl)-3-methyl-2-thiophenecarboxamide(350998-32-2)
• EPA Substance Registry System: 5-amino-4-cyano-N-(2-methoxyphenyl)-3-methyl-2-thiophenecarboxamide(350998-32-2)

Safety Data

• Hazardous Substances Data: 350998-32-2(Hazardous Substances Data)

Upstream product

• 90-04-0 2-methoxy-phenylamine 

Relevant articles and documents

Effective microwave synthesis of bioactive thieno[2,3-d]pyrimidines

A series of novel 2-Amino-3-cyanothiophenes (2a-2j) were synthesized using heterogeneous base (K2CO3) supported Gewald reaction. Cyclization of 2a-j with formamide and urea in conventional heating as well as microwave irradiation gave thieno[2,3-d]pyrimidines (3a-3j) and thieno[2,3-d]pyrimidin-2(1H)-ones(4a-4j) respectively. The reaction rates were faster and yields were higher in the microwave conditions. The structures of the compounds were confirmed with elemental analysis, mass spectral analysis, FTIR, 1H NMR and 13C NMR techniques. All the synthesized compounds were subjected to antimicrobial activity (MIC) in vitro by broth dilution method and exhibited a moderate antimicrobial activity.