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2,5-Bis(trifluoromethyl)benzenesulfonyl chloride is an organosulfur compound with the chemical formula C8H3ClF6O2S. It features a sulfonyl chloride functional group (-SO2Cl) attached to a benzene ring, which is substituted with two trifluoromethyl (-CF3) groups. This chemical is commonly used as a reagent in organic synthesis, enabling the formation of various derivatives for applications in pharmaceuticals, agrochemicals, and specialty chemicals.

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  • 351003-22-0 Structure
  • Basic information

    1. Product Name: 2,5-BIS(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE
    2. Synonyms: 2,5-BIS(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE;2,5-BIS(TRIFLUOROMETHYL)BENZENESULPHONYL CHLORIDE;TRANS-(1R,2R)-N,N''-DIMETHYL-1,2-CYCLOHEXANEDIAMINE;2,5-bis(trifluoroMethyl)benzene-1-sulfonyl chloride;2,5-Bis(trifluoromethyl)benzenesulfonyl chloride 97%
    3. CAS NO:351003-22-0
    4. Molecular Formula: C8H3ClF6O2S
    5. Molecular Weight: 312.62
    6. EINECS: -0
    7. Product Categories: Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds
    8. Mol File: 351003-22-0.mol
  • Chemical Properties

    1. Melting Point: 59-63 °C(lit.)
    2. Boiling Point: 277.6 °C at 760 mmHg
    3. Flash Point: 121.7 °C
    4. Appearance: /
    5. Density: 1.503 g/cm3
    6. Vapor Pressure: 0.00112mmHg at 25°C
    7. Refractive Index: 1.494
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. Sensitive: Hygroscopic
    11. CAS DataBase Reference: 2,5-BIS(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE(CAS DataBase Reference)
    12. NIST Chemistry Reference: 2,5-BIS(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE(351003-22-0)
    13. EPA Substance Registry System: 2,5-BIS(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE(351003-22-0)
  • Safety Data

    1. Hazard Codes: C
    2. Statements: 34
    3. Safety Statements: 26-27-36/37/39-45
    4. RIDADR: UN 3261 8/PG 2
    5. WGK Germany: 3
    6. RTECS:
    7. HazardClass: 8
    8. PackingGroup: III
    9. Hazardous Substances Data: 351003-22-0(Hazardous Substances Data)

351003-22-0 Usage

Uses

Used in Organic Synthesis:
2,5-Bis(trifluoromethyl)benzenesulfonyl chloride is used as a reagent in organic synthesis for its ability to participate in various chemical reactions. The presence of the sulfonyl chloride and trifluoromethyl groups allows it to form a variety of derivatives, which can be further utilized in the production of pharmaceuticals, agrochemicals, or other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,5-Bis(trifluoromethyl)benzenesulfonyl chloride is used as a building block for the synthesis of drug candidates. Its unique functional groups enable the development of novel compounds with potential therapeutic properties.
Used in Agrochemical Industry:
2,5-Bis(trifluoromethyl)benzenesulfonyl chloride is also used in the agrochemical industry as a precursor for the synthesis of active ingredients in pesticides or herbicides. Its chemical properties allow for the creation of compounds with targeted pest control capabilities.
Used in Specialty Chemicals Production:
In the production of specialty chemicals, 2,5-Bis(trifluoromethyl)benzenesulfonyl chloride serves as an intermediate or a key component in the synthesis of various high-value compounds. Its versatility in chemical reactions contributes to the development of innovative specialty chemicals for diverse applications.
It is important to handle 2,5-Bis(trifluoromethyl)benzenesulfonyl chloride with care, as it can be harmful if swallowed, inhaled, or comes in contact with the skin. Proper safety measures should be taken during its use in laboratories and industrial settings.

Check Digit Verification of cas no

The CAS Registry Mumber 351003-22-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,1,0,0 and 3 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 351003-22:
(8*3)+(7*5)+(6*1)+(5*0)+(4*0)+(3*3)+(2*2)+(1*2)=80
80 % 10 = 0
So 351003-22-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H5ClF2O3S/c8-14(11,12)6-3-1-5(2-4-6)13-7(9)10/h1-4,7H

351003-22-0 Well-known Company Product Price

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  • Alfa Aesar

  • (L19878)  2,5-Bis(trifluoromethyl)benzenesulfonyl chloride, 97%   

  • 351003-22-0

  • 1g

  • 568.0CNY

  • Detail
  • Alfa Aesar

  • (L19878)  2,5-Bis(trifluoromethyl)benzenesulfonyl chloride, 97%   

  • 351003-22-0

  • 5g

  • 2029.0CNY

  • Detail
  • Aldrich

  • (549002)  2,5-Bis(trifluoromethyl)benzenesulfonylchloride  97%

  • 351003-22-0

  • 549002-1G

  • 893.88CNY

  • Detail
  • Aldrich

  • (549002)  2,5-Bis(trifluoromethyl)benzenesulfonylchloride  97%

  • 351003-22-0

  • 549002-5G

  • 2,919.15CNY

  • Detail

351003-22-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,5-BIS(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE

1.2 Other means of identification

Product number -
Other names 2,5-Bis(trifluoromethyl)benzenesulfonyl chloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:351003-22-0 SDS

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