351003-38-8 Usage
Description
3-(Difluoromethoxy)benzenesulfonyl Chloride is an organic chemical compound characterized by its unique structure, which features a benzene ring with a difluoromethoxy group and a sulfonyl chloride group. 3-(DIFLUOROMETHOXY)BENZENESULFONYL CHLORIDE is known for its reactivity and is commonly utilized in the synthesis of various pharmaceutical compounds.
Uses
Used in Pharmaceutical Industry:
3-(Difluoromethoxy)benzenesulfonyl Chloride is used as a synthetic reagent for the preparation of phenoxypyridylpyrimidine derivatives. These derivatives are known as inositol requiring enzyme 1 (IRE1) activity modulators, which play a crucial role in the development of novel therapeutic strategies for various diseases, including cancer and neurodegenerative disorders.
Application Reason:
The use of 3-(Difluoromethoxy)benzenesulfonyl Chloride in the pharmaceutical industry is primarily due to its ability to facilitate the synthesis of phenoxypyridylpyrimidine derivatives. These derivatives have shown potential as modulators of IRE1 activity, which is an essential protein involved in cellular stress response pathways. By modulating IRE1 activity, these compounds can potentially help in the development of treatments for diseases where IRE1 plays a significant role in their progression.
Check Digit Verification of cas no
The CAS Registry Mumber 351003-38-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,1,0,0 and 3 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 351003-38:
(8*3)+(7*5)+(6*1)+(5*0)+(4*0)+(3*3)+(2*3)+(1*8)=88
88 % 10 = 8
So 351003-38-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H5ClF2O3S/c8-14(11,12)6-3-1-2-5(4-6)13-7(9)10/h1-4,7H
