351003-46-8 Usage
General Description
3-Bromo-5-(trifluoromethyl)benzenesulfonyl chloride is a chemical compound with the formula C7H3BrClF3O2S. It is a sulfonyl chloride derivative with a bromine atom located at the 3-position and a trifluoromethyl group at the 5-position of the benzene ring. 3-BROMO-5-(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE is widely used as a versatile building block in organic synthesis, particularly in the production of pharmaceuticals, agrochemicals, and specialty chemicals. It is a reactive and highly electrophilic reagent that is commonly used in the synthesis of sulfonamides and other biologically active compounds. Additionally, it serves as a key intermediate in the manufacturing of dyes and other specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 351003-46-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,1,0,0 and 3 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 351003-46:
(8*3)+(7*5)+(6*1)+(5*0)+(4*0)+(3*3)+(2*4)+(1*6)=88
88 % 10 = 8
So 351003-46-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H3BrClF3O2S/c8-5-1-4(7(10,11)12)2-6(3-5)15(9,13)14/h1-3H
351003-46-8Relevant articles and documents
Design and synthesis of benzenesulfonamide derivatives as potent anti-influenza hemagglutinin inhibitors
Tang, Guozhi,Lin, Xianfeng,Qiu, Zongxing,Li, Wentao,Zhu, Lei,Wang, Lisha,Li, Shaohua,Li, Haodong,Lin, Wenbin,Yang, Mei,Guo, Tao,Chen, Li,Lee, Daniel,Wu, Jim Z.,Yang, Wengang
supporting information; experimental part, p. 603 - 607 (2011/10/09)
Structural optimization of salicylamide-based hemagglutinin (HA) inhibitor 1 resulted in the identification of cis-3-(5-hydroxy-1,3,3- trimethylcyclohexylmethylamino)benzenesulfonamide 28 and its derivatives as potent anti-influenza agents. The lead compo