35102-16-0

Usage

Drug class

Psychoactive drug, 1,2,4-triazine class of compounds

Primary uses

Treatment of sleep disorders, anxiety

Mechanism of action

Enhances the activity of gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits the activity of the central nervous system

Effects

Sedative, hypnotic, calming

Additional properties

Potential neuroprotective and antidepressant effects

Legal status

Restricted use in many countries, not approved for medical use in some regions

Safety concerns

Potential for misuse and abuse

Upstream product

• 28735-27-5 3-methylthio-5-phenyl-1,2,4-triazine 
• 74-88-4 methyl iodide 

Relevant academic research and scientific papers

Comparison of non-covalent interactions and spectral properties in 1-methyl-3-methylthio-5-phenyl-1,2,4-triazinium mono- and tetraiodide crystals

The reaction of 1-methyl-3-methylthio-5-phenyl-1,2,4-triazinium (MTPT) iodide with diiodine in a solution leads to monoiodide crystal structure that in excess of iodine gives the unusual tetraiodide anion with two central iodine atoms in disorder. The bonding within the anion has been characterized as I–…I2…I–; the existence of the bound iodine molecule inside has been proven by the characteristic band in experimental and calculated Raman spectra. Non-covalent interactions of MTPT in considered crystal structures are different. Monoiodide anion as a strong electron donor allows the formation of the S…I chalcogen bonds that are absent in tetraiodide structure. The features of halogen bonds within the I4 2– anion are?also performed.