351020-30-9Relevant academic research and scientific papers
The asymmetric synthesis of (2S,3R)-capreomycidine
DeMong, Duane E.,Williams, Robert M.
, p. 3529 - 3532 (2007/10/03)
An improved asymmetric synthesis of the guanidine-containing amino acid (2S,3R)-capreomycidine has been achieved in seven steps and 28% overall yield. The key synthetic step involved a Mannich-type reaction between a chiral glycine aluminum enolate and the benzyl-imine of 3-tert-butyldimethylsiloxy-propionaldehyde.
