35105-74-9

Upstream product

• 513-81-5 2,3-dimethyl-buta-1,3-diene 
• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 18214-56-7 3,4-dimethyl-3-sulfolene 
• 18214-57-8 3,4-bis-(bromomethyl)-2,5-dihydrothiophene 1,1-dioxide 
• 100-46-9 benzylamine 

Downstream Products

• 50586-28-2 5-benzyloxycarbonyl-3,4,5,6-tetrahydro-1H-thieno<3,4-c>pyrrole 2,2-dioxide 
• 144425-41-2 1-Benzyl-1,6,9,9b-tetrahydro-benzo[g]indole-2,3,3a,4,7,8-hexacarboxylic acid hexamethyl ester 
• 144442-90-0 9-(Toluene-4-sulfonyl)-1,4,5,8-tetrahydro-1,4-epiazano-naphthalene-2,3,6,7-tetracarboxylic acid tetramethyl ester 
• 144425-44-5 1,4,5,8-Tetrahydro-1,4-epiazano-naphthalene-2,3,6,7,9-pentacarboxylic acid benzyl ester tetramethyl ester 
• 144425-45-6 9-Benzoyl-1,4,5,8-tetrahydro-1,4-epiazano-naphthalene-2,3,6,7-tetracarboxylic acid tetramethyl ester 
• 144425-40-1 7-Benzyl-5,6-dimethylene-7-aza-bicyclo[2.2.1]hept-2-ene-2,3-dicarboxylic acid dimethyl ester 
• 144425-33-2 3,4,5,6-tetrahydro-5-(p-tolylsulfonyl)-1H-thieno<3,4-c>pyrrole 2,2-dioxide 
• 144425-37-6 3,5-dihydro-5-(p-tolylsulfonyl)-1H-thieno<3,4-c>pyrrole 2,2-dioxide 
• 144425-35-4 5-benzyloxycarbonyl-3,5-dihydro-1H-thieno<3,4-c>pyrrole 2,2-dioxide 
• 144425-34-3 5-benzoyl-3,4,5,6-tetrahydro-1H-thieno<3,4-c>pyrrole 2,2-dioxide 
• 144425-38-7 5-benzoyl-3,5-dihydro-1H-thieno<3,4-c>pyrrole 2,2-dioxide 
• 144425-31-0 5-benzyl-3,5-dihydro-1H-thieno<3,4-c>pyrrole 2,2-dioxide 
• 50586-27-1 5-benzyl-hexahydro-thieno[3,4-c]pyrrole 2,2-dioxide 

Relevant academic research and scientific papers

2-PHENYL-5-HETEROCYCLYL-TETRAHYDRO-2H-PYRAN-3-AMINE COMPOUNDS FOR USE IN THE TREATMENT OF DIABETES AND ITS ASSOCIATED DISORDERS

The present invention relates to novel compounds of the general formula (I) their tautomeric forms, their enantiomers, their diastereoisomers, their pharmaceutically accepted salts, or pro-drugs thereof, which are useful for the treatment or prevention of diabetes mellitus (DM), obesity and other metabolic disorders. The invention also relates to process for the manufacture of said compounds, and pharmaceutical compositions containing them and their use.

New Building Blocks, 3,5-Dihydro-1H-thienopyrrole 2,2-Dioxides; Preparation and their Diels-Alder Reaction with Dimethyl Acetylenedicarboxylate

New building blocks, 3,5-dihydro-1H-thienopyrrole 2,2-dioxides 3, have been prepared by the oxidation of their corresponding pyrroline derivates 4 with DDQ or Chemical MnO2.The Diels-Alder reaction of 3 with dimethyl acetylenedicarboxylate gave new types of compounds: 7-aza-2,3-dimethylenenorbornenes A, the 1:2 adducts B, 1a,3a,6,9-tetrahydrobenzindoles C, and dihydroindolosulfolene D depending on the reaction conditions and the N-substituents.The reaction of 3 with bis(tert-butylsulfonyl)acetylene was also described.

New Building Blocks, 3,5-Dihydro-1H-thienopyrrole 2,2-Dioxides; Preparation and their Diels-Alder Reaction with Dimethyl Acetylenedicarboxylate

New building blocks, 3,5-dihydro-1H-thienopyrrole 2,2-dioxides 1, have been prepared and react with dimethyl acetylenedicarboxylate to give new types of compound; 7-aza-2,3-dimethylenenorbornene A, the 1 : 2 adduct B, 1a,3a,6,9-tetrahydrobenzindole C, and dihydroindolosulfolene D depending on the reaction conditions and the N-substituent.