351060-19-0Relevant academic research and scientific papers
Synthesis of β-1,4-di-d-mannuronic acid glycosides as potential ligands for toll-like receptors
Jiang, Zi-Hua,Xu, Rongsong,Wilson, Charlene,Brenk, Agnes
, p. 2915 - 2918 (2008/02/03)
Toll-like receptors (TLRs) play important roles in host immune defense, and synthetic TLR ligands are useful therapeutic agents for a variety of diseases including infection, inflammation, and cancers. Alginates are strong immune stimulants mediated by TL
Direct chemical synthesis of the β-D-mannans: The β-(1→2) and β-(1→4) series
Crich, David,Banerjee, Abhisek,Yao, Qingjia
, p. 14930 - 14934 (2007/10/03)
The direct syntheses of β-(1→2)-mannooctaose and of β-(1→4)-mannohexaose are reported by means of 4,6-O-benzylidene- protected β-mannosyl donors. The synthesis of the (1→2)-mannan was achieved by means of the sulfoxide coupling protocol, whereas the (1→4)
Direct chemical synthesis of the β-mannans: Linear and block syntheses of the alternating β-(1→3)-β-(1→4)-mannan common to Rhodotorula glutinis, Rhodotorula mucilaginosa, and Leptospira biflexa
Crich, David,Li, Wenju,Li, Hongmei
, p. 15081 - 15086 (2007/10/03)
Two stereocontrolled syntheses of a methyl glycoside of an alternating β-(1→4)-β-(1→3)-mannohexaose, representative of the mannan from Rhodotorula glutinis, Rhodotorula mucilaginosa, and Leptospira biflexa, are described. Both syntheses employ a combinati
