3511-89-5

Basic information

• Product Name: 2,3,5,6-TETRAFLUORO-4-NITROPYRIDINE
• Synonyms: 2,3,5,6-TETRAFLUORO-4-NITROPYRIDINE;Pyridine, 2,3,5,6-tetrafluoro-4-nitro- (7CI,8CI,9CI)
• CAS NO: 3511-89-5
• Molecular Formula: C₅F₄N₂O₂
• Molecular Weight: 196.06
• Product Categories: PYRIDINE
• Mol File: 3511-89-5.mol

Chemical Properties

• Melting Point: 152-154
• Boiling Point: 152-154
• Flash Point: 103.7 °C
• Appearance: /
• Density: 1.76 g/cm³
• Vapor Pressure: 0.0396mmHg at 25°C
• Refractive Index: 1.466
• CAS DataBase Reference: 2,3,5,6-TETRAFLUORO-4-NITROPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,5,6-TETRAFLUORO-4-NITROPYRIDINE(3511-89-5)
• EPA Substance Registry System: 2,3,5,6-TETRAFLUORO-4-NITROPYRIDINE(3511-89-5)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 3511-89-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2,3,5,6-TETRAFLUORO-4-NITROPYRIDINE is used as an intermediate in the synthesis of pharmaceuticals for its ability to enhance the properties of the final drug products.
Used in Agrochemical Industry:
2,3,5,6-TETRAFLUORO-4-NITROPYRIDINE is used as an intermediate in the synthesis of agrochemicals to improve the effectiveness of these compounds in agricultural applications.
Used in Specialty Chemicals Manufacturing:
2,3,5,6-TETRAFLUORO-4-NITROPYRIDINE is used in the manufacturing of specialty chemicals due to its strong electron-withdrawing properties, which contribute to the unique characteristics of the resulting products.
Used in Organic Synthesis:
2,3,5,6-TETRAFLUORO-4-NITROPYRIDINE serves as a building block in organic synthesis, allowing for the creation of a wide range of organic compounds with diverse applications.

InChI:InChI=1/C5F4N2O2/c6-1-3(11(12)13)2(7)5(9)10-4(1)8

Upstream product

• 1682-20-8 2,3,5,6-tetrafluoropyridin-4-amine 
• 700-16-3 Pentafluoropyridine 
• 105608-95-5 4-hydroxylamino-2,3,5,6-tetrafluoropyridine 

Downstream Products

• 1682-20-8 2,3,5,6-tetrafluoropyridin-4-amine 
• 105608-95-5 4-hydroxylamino-2,3,5,6-tetrafluoropyridine 
• 700-16-3 Pentafluoropyridine 
• 23862-40-0 2,4,5-triamino-difluoropyridine 
• 6256-96-8 3,4-diamino-2,5,6-trifluoropyridine 
• 24316-34-5 2,3,5,6-tetrafluoro-4-(phenylsulfanyl)pyridine 

Relevant articles and documents

Sequential continuous flow processes for the oxidation of amines and azides by using HOF·MeCN

The generation and use of the highly potent oxidising agent HOF·MeCN in a controlled single continuous flow process is described. Oxidations of amines and azides to corresponding nitrated systems by using fluorine gas, water and acetonitrile by sequential gas-liquid/liquid-liquid continuous flow procedures are reported. Oxidation in flow: The oxidation of amines and azides to the corresponding nitrated systems by using fluorine gas, water and acetonitrile by sequential gas-liquid/liquid-liquid continuous flow procedures are reported. Copyright

N-(POLYFLUOROARYL)-HIDROXYLAMINES. SYNTHESIS AND PROPERTIES

Fluorine-containing N-arylhydroxylamines have been obtained by the reaction of hydroxylamine or its N- and O-derivatives on polyfluorinated benzenes and pentafluoropyridine.The influence of fluorine atoms on the reactivity of hydroxylamino group has been investigated.The reaction of N-polyflouroarylhydroxylamines with aldehydes has been shown not to occur, whereas their reaction with nitrosobenzenes leads to azoxybenzenes and with Lewis acids leads to corresponding nitrosobenzenes, azoxybenzenes and anilines.The action of acids on 2,3,5,6-tetrafluorophenylhydroxylamine leads to the acid-catalyzed rearrangement of the latter into 4-amino-2,3,5,6-tetrafluorophenol.C,N-Diarylnitrones have been obtained by the oxidation with MnO2 of fluorine-containing arylhydroxylamines possessing the CH-fragment in an α-position.