35121-47-2

Basic information

• Product Name: 5-(phenoxymethyl)-3-phenyl-4,5-dihydro-1,2-oxazole
• Synonyms: 5-(phenoxymethyl)-3-phenyl-4,5-dihydro-1,2-oxazole
• CAS NO: 35121-47-2
• Molecular Weight: 253.301
• Mol File: 35121-47-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-(phenoxymethyl)-3-phenyl-4,5-dihydro-1,2-oxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(phenoxymethyl)-3-phenyl-4,5-dihydro-1,2-oxazole(35121-47-2)
• EPA Substance Registry System: 5-(phenoxymethyl)-3-phenyl-4,5-dihydro-1,2-oxazole(35121-47-2)

Safety Data

• Hazardous Substances Data: 35121-47-2(Hazardous Substances Data)

Upstream product

• 1746-13-0 allyl phenyl ether 
• 932-90-1 Benzaldoxime 
• 68843-67-4 (E)-1-phenylbut-3-en-1-one oxime 
• 139-02-6 sodium phenoxide 
• 873-67-6 benzonitrile oxide 

Downstream Products

• 35121-46-1 5-phenoxymethyl-3-phenyl-isoxazole 

Relevant articles and documents

Room temperature iron(ii)-catalyzed radical cyclization of unsaturated oximes with hypervalent iodine reagents

Here, we disclose an iron(ii)-catalyzed I-O bond cleavage of Koser's hypervalent iodine reagents (HIRs) that initiated the radical cyclization of unsaturated oximes at room temperature. This strategy is successfully applied for the construction of the isoxazoline backbone in an efficient manner. In particular, the direct introduction of a TsO group into products facilitates their late-stage transformations in organic synthesis.

Enhanced rate of intramolecular nitrile oxide cycloaddition and rapid synthesis of isoxazoles and isoxazolines

An enhanced rate of intramolecular nitrile oxide cycloaddition and hence a rapid synthesis of isoxazoles and isoxazolines is described. Formation of nitrile oxides from oximes using only 1 or 2 Eq (equivalents) of aqueous sodium hypochlorite solution is also described. Springer-Verlag 2010.