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351330-42-2

2-[(5-FLUORESCEINYL)AMINOCARBONYL]ETHYL METHANETHIOSULFONATE, also known as MTS-fluorophores, is a thiol-specific fluorescent probe derived from hydrolyzable tannins. It is a yellow solid with a maximum absorption at 492nm and maximum emission at 515nm, possessing a molar absorptivity of 75 x 10^-3. Its chemical structure allows it to interact with biopolymers and macromolecules, making it a valuable tool in various research applications.

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  • 351330-42-2 Structure

  • Basic information

    1. Product Name: 2-[(5-FLUORESCEINYL)AMINOCARBONYL]ETHYL METHANETHIOSULFONATE
    2. Synonyms: MTS-4-FLUORESCEIN;2-[(5-FLUORESCEINYL)AMINOCARBONYL]ETHYL METHANETHIOSULFONATE;Methanesulfonothioic Acid S-[3-[(3',6'-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)aMino]-3-oxopropyl] Ester;2-[(5-Fluoresceinyl)-aminocarbonyl]-ethyl-methanthiosulfonat
    3. CAS NO:351330-42-2
    4. Molecular Formula: C24H19NO8S2
    5. Molecular Weight: 513.54
    6. EINECS: N/A
    7. Product Categories: Fluorescent Labels & Indicators;MTS & Sulfhydryl Active Reagents
    8. Mol File: 351330-42-2.mol

  • Chemical Properties

    1. Melting Point: >180°C dec.
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: -20°C Freezer
    8. Solubility: DMSO (Slightly), Methanol (Slightly)
    9. Stability: Light/Moisture Sensitive; Desiccate and Store at -20°C
    10. CAS DataBase Reference: 2-[(5-FLUORESCEINYL)AMINOCARBONYL]ETHYL METHANETHIOSULFONATE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-[(5-FLUORESCEINYL)AMINOCARBONYL]ETHYL METHANETHIOSULFONATE(351330-42-2)
    12. EPA Substance Registry System: 2-[(5-FLUORESCEINYL)AMINOCARBONYL]ETHYL METHANETHIOSULFONATE(351330-42-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 351330-42-2(Hazardous Substances Data)

351330-42-2 Usage

Uses

Used in Ion Channel and Protein Topology Research:
2-[(5-FLUORESCEINYL)AMINOCARBONYL]ETHYL METHANETHIOSULFONATE is used as a thiol-specific fluorescent probe for ion channel and protein topology research. It is particularly useful in studying conformational changes in proteins, as the fluorescence of the probe can change during these changes.
Used in Real-Time Monitoring of Conformational Changes:
In the field of molecular biology, 2-[(5-FLUORESCEINYL)AMINOCARBONYL]ETHYL METHANETHIOSULFONATE is used as a real-time monitoring tool for conformational changes in proteins. The probe's fluorescence properties allow researchers to track these changes, providing valuable insights into protein dynamics and function.
Used in Fluorescence Lifetime Studies:
2-[(5-FLUORESCEINYL)AMINOCARBONYL]ETHYL METHANETHIOSULFONATE is also used in fluorescence lifetime studies, where it can provide information regarding distances and molecular motion within a protein molecule. This application is particularly relevant in the fields of biophysics and structural biology, where understanding protein structure and dynamics is crucial for elucidating their function and potential as therapeutic targets.

Check Digit Verification of cas no

The CAS Registry Mumber 351330-42-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,1,3,3 and 0 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 351330-42:
(8*3)+(7*5)+(6*1)+(5*3)+(4*3)+(3*0)+(2*4)+(1*2)=102
102 % 10 = 2
So 351330-42-2 is a valid CAS Registry Number.

351330-42-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[(5-Fluoresceinyl)aminocarbonyl]ethyl Methanethiosulfonate

1.2 Other means of identification

Product number -
Other names S-{3-[(3',6'-Dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthen]- 5-yl)amino]-3-oxopropyl} methanesulfonothioate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:351330-42-2 SDS

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