351365-93-0Relevant academic research and scientific papers
Efficient synthesis of 6-aryl-2-chloronicotinic acids via Pd catalyzed regioselective suzuki coupling of 2,6-dichloronicotinic acid
Ma, Mingliang,Li, Chengwei,Li, Xiaoyan,Wen, Ke,Liu, Yahu A.
, p. 1847 - 1849 (2008)
(Chemical Equation Presented) A regioselective Suzuki coupling of 2,6-dichloronicotinic acid with aryl boronic acids to synthesize 6-aryl-2-chloronicotinic acids is described. Regioselectivity was achieved in aqueous dioxane using the routinely used catalyst Pd(PPh3) 4.
