351412-73-2

Upstream product

• 351412-72-1 [(2R,3R)-2,3-dihydroxy-3-methylpent-4-ynyl](4-methylphenyl)sulfonate 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 351412-68-5 Toluene-4-sulfonic acid (S)-2-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-hydroxy-4-trimethylsilanyl-but-3-ynyl ester 
• 351412-69-6 (4R)-4-[(1S)-1-trimethylsilylethynyl(2-oxiranyl)]-2,2-dimethyl-1,3-dioxolane 
• 351412-70-9 (2R)-2-[(1R)-3,3-dimethyl(2,4-dioxolanyl)]-4-trimethylsilylbut-3-yn-2-ol 
• 351412-71-0 (2R,3R)-3-methylpent-4-yne-1,2,3-triol 

Downstream Products

• 351412-74-3 [(2R,3R)-2,3-bis(tert-butyldimethylsilyloxy)-6-hydroxy-3-methyl-6-(1-(tert-butyldimethylsilyloxy)(2-naphthyl))hex-4-ynyl] (4-methylphenyl)sulfonate 

Relevant academic research and scientific papers

Selective intercalation of charge neutral intercalators into GG and CG steps: Implication of HOMO-LUMO interaction for sequence-selective drug intercalation into DNA

We have synthesized naphthopyranone epoxide 4 from D-isoascorbic acid together with its three diastereoisomers. DNA alkylation of ODNs containing 5′XGT3′ and 5′TGY3′ by 4 (11R, 13R), where X and Y are any nucleotide bases, occurred at all G residues excep