351420-01-4Relevant academic research and scientific papers
Titanium isopropoxide promoted tandem self-cross and ring-closing metathesis approach for the synthesis of macrotetralides
Muthusamy, Sengodagounder,Azhagan, Datshanamoorthy
, p. 363 - 370 (2014/01/23)
A new approach is demonstrated for the synthesis of macrotetralides through an olefin metathesis reaction using Grubbs' second-generation catalyst with titanium isopropoxide as a cocatalyst. This study demonstrates a tandem self-cross and ring-closing metathesis approach to form macrocyclic ring systems with excellent (E) selectivity. The reaction was optimized with regard to functional group, catalyst, solvent, Lewis acid, concentration, and temperature. A new approach is demonstrated for the synthesis of macrotetralides through tandem self-cross and ring-closing metathesis reactions using Grubbs' second-generation catalyst and titanium isopropoxide. Copyright
Titanium Isopropoxide Promoted Tandem Self-Cross and Ring-Closing Metathesis Approach for the Synthesis of Macrotetralides
Muthusamy, Sengodagounder,Azhagan, Datshanamoorthy
supporting information, p. 363 - 370 (2015/10/05)
A new approach is demonstrated for the synthesis of macrotetralides through an olefin metathesis reaction using Grubbs' second-generation catalyst with titanium isopropoxide as a cocatalyst. This study demonstrates a tandem self-cross and ring-closing metathesis approach to form macrocyclic ring systems with excellent (E) selectivity. The reaction was optimized with regard to functional group, catalyst, solvent, Lewis acid, concentration, and temperature. A new approach is demonstrated for the synthesis of macrotetralides through tandem self-cross and ring-closing metathesis reactions using Grubbs' second-generation catalyst and titanium isopropoxide.
