351422-29-2

Basic information

• Product Name: (R)-2-Amino-2-carboxyethylmethanethiosulfonate
• Synonyms: Cys-MTS, Cysteinemethanethiosulfonate;S-(Methylsulfonyl)-L-cysteine
• CAS NO: 351422-29-2
• Molecular Formula: C4H9NO4S2
• Molecular Weight: 199.25
• Product Categories: MTS and Sulfhydryl Active Reagents;MTS & Sulfhydryl Active Reagents;Amino Acids & Derivatives
• Mol File: 351422-29-2.mol
• Article Data: 2

Chemical Properties

• Melting Point: 158°C dec.
• Boiling Point: 454.09 °C at 760 mmHg
• Flash Point: 228.425 °C
• Appearance: off-white solid
• Density: 1.554 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.579
• Storage Temp.: -20?C Freezer
• CAS DataBase Reference: (R)-2-Amino-2-carboxyethylmethanethiosulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-Amino-2-carboxyethylmethanethiosulfonate(351422-29-2)
• EPA Substance Registry System: (R)-2-Amino-2-carboxyethylmethanethiosulfonate(351422-29-2)

Safety Data

• Hazardous Substances Data: 351422-29-2(Hazardous Substances Data)

Usage

Chemical Properties

Off-White Solid

Uses

Different sources of media describe the Uses of 351422-29-2 differently. You can refer to the following data:
1. An interesting MTS compound that contains both amine and carboxylic acid groups as part of it structure
2. An interesting MTS compound that contains both amine and carboxylic acid groups as part of it’s structure.

InChI:InChI=1/C4H9NO4S2/c1-11(8,9)10-2-3(5)4(6)7/h3H,2,5H2,1H3,(H,6,7)/t3-/m0/s1

Upstream product

• 52-89-1 l-cysteine hydrochloride 
• 20277-69-4 sodium methansulfinate 

Relevant articles and documents

Convenient synthesis of multifunctional EDTA-based chiral metal chelates substituted with an S-mesylcysteine

We describe the synthetic route to ethylenediaminetetraacetic acid (EDTA) derivatives that can be attached to surface-exposed thiol functional groups of cysteine residues in proteins, via a methylthiosulfonate moiety that is connected in a stereochemically unique way to the C-1 carbon atom of EDTA. Such compounds can be used to align proteins in solution without the need to add liquid crystalline media, and are, therefore, of great interest for the NMR spectroscopic analysis of biomolecules. The binding constant for the paramagnetic tag to lanthanide ions was determined by measuring luminescence. For the Tb+3-ligand complex, a Kb value of 6.5×1017-1 was obtained. This value is in excellent agreement with literature values for the related EDTA compound. In addition, it could be shown that there is no significant reduction in the luminescence intensity upon addition of a 104 excess of Ca2+ ions, indicating that this paramagnetic tag is compatible with buffers containing high concentrations of divalent alkaline earth ions.