3515-49-9 Usage
General Description
3-(4-Piperidylmethyl)-1H-indole, also known as PPI, is a chemical compound with the molecular formula C15H19N, consisting of a piperidylmethyl group attached to a 1H-indole ring. It is a heterocyclic compound with a ring structure containing nitrogen, which makes it useful in pharmaceutical research and drug development. PPI has been studied for its potential as a serotonin receptor agonist, and as a potential treatment for conditions such as anxiety, depression, and schizophrenia. The compound has also been investigated for its potential use in the treatment of Parkinson's disease and as a psychoactive substance. Further research is ongoing to explore its potential therapeutic applications and pharmacological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 3515-49-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,5,1 and 5 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 3515-49:
(6*3)+(5*5)+(4*1)+(3*5)+(2*4)+(1*9)=79
79 % 10 = 9
So 3515-49-9 is a valid CAS Registry Number.
InChI:InChI=1/C14H18N2/c1-2-4-14-13(3-1)12(10-16-14)9-11-5-7-15-8-6-11/h1-4,10-11,15-16H,5-9H2
3515-49-9Relevant articles and documents
-
Gray
, p. 1453 (1958)
-
3-(4-Piperidinylalkyl)indoles, Selective Inhibitors of Neuronal 5-Hydroxytryptamine Uptake
Gueremy, Claude,Audiau, Francois,Champseix, Alain,Uzan, Andre,Fur, Gerard Le,Rataud, Jean
, p. 1306 - 1310 (2007/10/02)
A series 3-(4-piperidinylalkyl)indoles was synthesized and tested as uptake inhibitors of biogenic amines.Some of these compounds are potent and very selective in blocking the 5-hydroxytryptamine (5-HT) uptake, as evidenced by biochemical data and behavioral tests.A discussion on structure-activity relationships is given.The most interesting member of the series, indalpine, 3-indole (1), was selected for clinical studies.
