35160-10-2 Usage
Uses
Used in Organic Synthesis:
(4,5-DIHYDRO-THIAZOL-2-YL)-O-TOLYL-AMINE is used as a building block in organic synthesis for the creation of various bioactive compounds. Its distinctive structure allows it to be a key component in the development of new chemical entities.
Used in Pharmaceutical Research:
In pharmaceutical research, (4,5-DIHYDRO-THIAZOL-2-YL)-O-TOLYL-AMINE is utilized for its potential biological activity. Researchers explore its properties to assess its efficacy in different therapeutic areas, potentially leading to the discovery of new drugs or drug candidates.
Used in Medicinal Chemistry:
(4,5-DIHYDRO-THIAZOL-2-YL)-O-TOLYL-AMINE is employed in medicinal chemistry as a starting point for the design and synthesis of novel therapeutic agents. Its unique structural features can be leveraged to create molecules with specific biological targets and desired pharmacological effects.
Used in Drug Development:
As a compound with potential pharmacological properties, (4,5-DIHYDRO-THIAZOL-2-YL)-O-TOLYL-AMINE may be used in drug development processes. It can be optimized and modified to enhance its therapeutic potential, leading to the creation of new medications for various diseases and conditions.
The exact uses and properties of (4,5-DIHYDRO-THIAZOL-2-YL)-O-TOLYL-AMINE may vary depending on the specific context and application within these industries. Its versatility and potential make it a promising candidate for further exploration and development in the fields of organic synthesis and pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 35160-10-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,1,6 and 0 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 35160-10:
(7*3)+(6*5)+(5*1)+(4*6)+(3*0)+(2*1)+(1*0)=82
82 % 10 = 2
So 35160-10-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H12N2S/c1-8-4-2-3-5-9(8)12-10-11-6-7-13-10/h2-5H,6-7H2,1H3,(H,11,12)
35160-10-2Relevant academic research and scientific papers
Synthesis and biological activity of novel symmetrical bis-2- phenyliminothiazolidine derivatives
Li, Gang-Yue,Qian, Xu-Hong,Yan, Sheng-Gang,Cui, Jing-Nan,Huang, Qing-Chun,Zhang, Rong,Liu, Feng-Yu,Cui, Da-Wei
, p. 2851 - 2861 (2007/10/03)
A series of novel symmetrical bis-2-phenyliminothiazolidine derivatives were designed and synthesized. The structures of all the title compounds were characterized by 1H NMR and, in some cases, by 13C NMR, IR, and high-resolution mas
Synthesis and QSAR studies in 2-(N-aryl-N-aroyl)amino-4,5-dihydrothiazole derivatives as potential antithrombotic agents
Saxena, Anil K.,Pandey, Suresh K.,Seth,Singh,Dikshit,Carpy
, p. 2025 - 2034 (2007/10/03)
A series of 2-(N-aryl-N-aroyl)amino-4,5-dihydrothiazole derivatives have been synthesized via cyclocondensation of N-aryl thioureas with 2-bromoethylamine hydrobromide followed by the reaction of the product thus obtained with aroyl chlorides. Title compounds were evaluated for their antithrombotic activity in vivo in mice where one of these compound 29 provided 65% protection as compared to 77% protection offered by the standard Indomethacin. Quantitative Structure-Activity Relationship (QSAR) studies were performed on these compounds using physicochemical (hydrophobic, electronic, steric) parameter as independent and antithrombic activity as dependent parameter, where antithrombotic activity correlated best (r > 0.8) with electronic parameters (F, σ or μ) having high statistical significance > 99.9% (F2,22 > 15.0; F2,22α:0.001 = 11.0) suggesting that hydrophobic, steric and resonance factors are insignificant in this set of molecules for the activity.
