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H-TIC-OH, also known as (S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid, is an organic compound that serves as an intermediate in the synthesis of Quinapril, a widely used angiotensin-converting enzyme (ACE) inhibitor. It is characterized by its unique chemical structure, which includes a tetrahydroisoquinoline ring and a carboxylic acid functional group. This structure endows H-TIC-OH with specific chemical properties and reactivity, making it a valuable compound in the pharmaceutical industry.

35186-99-3

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35186-99-3 Usage

Uses

Used in Pharmaceutical Industry:
H-TIC-OH is used as a key intermediate in the synthesis of Quinapril, an ACE inhibitor medication. It plays a crucial role in the development of this drug, which is used for the treatment of hypertension, heart failure, and other cardiovascular conditions. H-TIC-OH's reactivity and structural features enable the formation of the final drug product, contributing to its therapeutic effects.
Used in Research and Development:
H-TIC-OH is also utilized in research and development efforts, particularly in the field of medicinal chemistry. Its unique structure and properties make it an interesting compound for studying the design and synthesis of new drugs targeting various diseases and conditions. Researchers can use H-TIC-OH as a starting material or a building block to create novel chemical entities with potential therapeutic applications.
Used in Quality Control and Regulatory Compliance:
In addition to its applications in drug synthesis and research, H-TIC-OH is also used in quality control and regulatory compliance processes within the pharmaceutical industry. As an impurity in Quinapril, it is essential to monitor and control the levels of H-TIC-OH in the final drug product to ensure safety, efficacy, and compliance with regulatory standards. This helps maintain the overall quality and integrity of the medication, protecting patients and meeting industry requirements.

Check Digit Verification of cas no

The CAS Registry Mumber 35186-99-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,1,8 and 6 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 35186-99:
(7*3)+(6*5)+(5*1)+(4*8)+(3*6)+(2*9)+(1*9)=133
133 % 10 = 3
So 35186-99-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H11NO2/c12-10(13)9-5-7-3-1-2-4-8(7)6-11-9/h1-4,9,11H,5-6H2,(H,12,13)

35186-99-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name H-TIC-OH

1.2 Other means of identification

Product number -
Other names D-tetrahydroisoquinoline carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:35186-99-3 SDS

35186-99-3Upstream product

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