351894-04-7

Basic information

• Product Name: (2E)-2-cyano-N-cyclohexyl-3-(4-hydroxyphenyl)prop-2-enamide
• Synonyms: (2E)-2-Cyano-N-cyclohexyl-3-(4-hydroxyphenyl)acrylamide; 2-propenamide, 2-cyano-N-cyclohexyl-3-(4-hydroxyphenyl)-, (2E)-
• CAS NO: 351894-04-7
• Molecular Formula: C₁₆H₁₈N₂O₂
• Molecular Weight: 270.3263
• Mol File: 351894-04-7.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 525.4°C at 760 mmHg
• Flash Point: 271.6°C
• Density: 1.2g/cm³
• Vapor Pressure: 1.17E-11mmHg at 25°C
• Refractive Index: 1.591
• CAS DataBase Reference: (2E)-2-cyano-N-cyclohexyl-3-(4-hydroxyphenyl)prop-2-enamide(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-2-cyano-N-cyclohexyl-3-(4-hydroxyphenyl)prop-2-enamide(351894-04-7)
• EPA Substance Registry System: (2E)-2-cyano-N-cyclohexyl-3-(4-hydroxyphenyl)prop-2-enamide(351894-04-7)

Safety Data

• Hazardous Substances Data: 351894-04-7(Hazardous Substances Data)

Usage

General Description

(2E)-2-cyano-N-cyclohexyl-3-(4-hydroxyphenyl)prop-2-enamide, also known as CX-4945, is a potent and selective small molecule inhibitor of protein kinase CK2. It has been shown to have potential therapeutic applications in cancer treatment, as CK2 is known to be overexpressed in many tumor types and plays a role in promoting cell growth and survival. CX-4945 has been studied in pre-clinical and clinical trials for its anti-cancer properties and has shown promising results in inhibiting tumor growth and metastasis. Additionally, it has also been investigated for its potential in treating other diseases such as neurodegenerative disorders and inflammation. Overall, CX-4945 shows potential as a targeted therapy for cancer and other diseases related to CK2 dysregulation.