35190-65-9

Basic information

• Product Name: Piperazine, 1,4-dimethyl-, 1,4-dioxide (9CI)
• Synonyms: Piperazine, 1,4-dimethyl-, 1,4-dioxide (9CI);1,4-Dimethylpiperazine 1,4-dioxide;N,N'-Dimethyldioxidopiperazine;N,N-dimethylpiperazine dioxide;NSC 367800
• CAS NO: 35190-65-9
• Molecular Formula: C6H14N2O2
• Molecular Weight: 146.18756
• Product Categories: PIPERAZINE
• Mol File: 35190-65-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 283-284℃
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• CAS DataBase Reference: Piperazine, 1,4-dimethyl-, 1,4-dioxide (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazine, 1,4-dimethyl-, 1,4-dioxide (9CI)(35190-65-9)
• EPA Substance Registry System: Piperazine, 1,4-dimethyl-, 1,4-dioxide (9CI)(35190-65-9)

Safety Data

• Hazardous Substances Data: 35190-65-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H14N2O2/c1-7(9)3-5-8(2,10)6-4-7/h3-6H2,1-2H3

Upstream product

• 106-58-1 N,N'-dimethylpiperazine 

Relevant articles and documents

Stereoselectivity in the Formation of Heterocyclic Amine Oxides

The stereoselectivity of the oxidation of N-alkylpiperidines was studied with the aid of the conformationally biassing 4-tert-butyl substituent.The stereoselectivity was always >95percent and showed little sensitivity to the nature of the N-alkyl substituent.The axial approach was found to be predominating stereochemical oxidation path.A brief study of the effects of solvent, temperature, and oxidant on the stereoselectivity was made.The 1,4-dimethylpiperazine system was investigated, and its oxidation at room temperature resulted in 100percent of trans-1,4-dimethylpiperazine 1,4-dioxide.A method to modulate the stereoselectivity in the formation of saturated heterocyclic amine oxides was developed by inverting the sequence of introduction of the nitrogen substituents.With cis-8-methyl-8-azabicyclononane oxidation is preferred from that side of the molecule which is sterically more hindered.