352030-80-9

Basic information

• Product Name: 1-(4-methoxy-phenyl)-3-propyl-thiourea
• Synonyms: 1-(4-methoxy-phenyl)-3-propyl-thiourea
• CAS NO: 352030-80-9
• Molecular Weight: 224.327
• Mol File: 352030-80-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(4-methoxy-phenyl)-3-propyl-thiourea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-methoxy-phenyl)-3-propyl-thiourea(352030-80-9)
• EPA Substance Registry System: 1-(4-methoxy-phenyl)-3-propyl-thiourea(352030-80-9)

Safety Data

• Hazardous Substances Data: 352030-80-9(Hazardous Substances Data)

Upstream product

• 628-30-8 n-Propyl isothiocyanate 
• 104-94-9 4-methoxy-aniline 
• 107-10-8 propylamine 
• 2284-20-0 4-Methoxyphenyl isothiocyanate 

Relevant articles and documents

Facile synthesis of phthalidyl fused spiro thiohydantoins through silica sulfuric acid induced oxidative rearrangement of ninhydrin adducts of thioureas

A one-pot three-component sequential synthetic protocol produces structurally and biologically important phthalidyl fused spiro N,N′-disubstituted thiohydantoins from readily available aromatic isothiocyanates, primary amines and ninhydrin. In this three-step synthesis while the initial two steps are catalyst-free, in the final step silica sulfuric acid (SSA) induces an oxidative rearrangement in [3.3.0]-bicyclic 1,2-diol adducts of ninhydrin and thioureas under solvent-free condition to generate the final products spiro-fused thiohydantoins. The adequate acidity of SSA in cooperation with moderate oxidizing property promotes a facile oxidative rearrangement in 1,2-diol intermediates to produce the spiro-fused thiohydantoins with diverse functionalities. Easy recyclability of SSA, good to excellent yield of the products, wider substrate scope, shorter reaction time, solvent-free two steps out of three and high atom economy make this method attractive and practicable.

Traceless synthesis of urea, semicarbazide and carbamate derivatives using Bromo-Wang resin and Bromo-Wang SynPhase Lantern

Traceless synthesis of urea, semicarbazide and carbamate derivatives has been carried out successfully on bromo-Wang resin and SynPhase Lantern. The synthetic route is simple and convenient to perform. Most of the products are obtained in high yields and purities after acidic cleavage.