35212-99-8

Usage

Uses

Used in Pharmaceutical Research and Drug Development:
5,6-Dimethoxy-benzo[b]thiophene-2-carboxylic acid methyl ester is used as a compound with potential pharmaceutical applications for its anti-inflammatory and antimicrobial properties. It is being studied for its potential applications in the treatment of various diseases and disorders.
Used in Anti-inflammatory Applications:
5,6-Dimethoxy-benzo[b]thiophene-2-carboxylic acid methyl ester is used as an anti-inflammatory agent, which can help in reducing inflammation and pain associated with various conditions.
Used in Antimicrobial Applications:
5,6-Dimethoxy-benzo[b]thiophene-2-carboxylic acid methyl ester is used as an antimicrobial agent, which can help in treating infections caused by bacteria and other microorganisms.

InChI:InChI=1/C12H12O4S/c1-14-8-4-7-5-11(12(13)16-3)17-10(7)6-9(8)15-2/h4-6H,1-3H3

Upstream product

• 5392-10-9 2-bromo-4,5-dimethoxybenzaldehyde 
• 2365-48-2 Methyl thioglycolate 
• 2316-26-9 3,4-dimethoxycinnamic acid 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 71797-90-5 methyl 3-chloro-5,6-dimethoxybenzo[b]thiophene-2-carboxylate 
• 700-96-9 3,4-dimethoxythiophenol 
• 193549-37-0 methyl 2-(3,4-dimethoxyphenylthio)acetate 
• 1649501-87-0 methyl (Z)-2-(3,4-dimethoxyphenylthio)-3-(dimethylamino)acrylate 
• 71924-62-4 2-fluoro-4,5-dimethoxybenzaldehyde 
• 23046-03-9 5,6-dimethoxy-benzo[b]thiophene-2-carboxylic acid 

Downstream Products

• 1295537-10-8 methyl 2-(5,6-dimethoxybenzo[b]thiophene-2-carboxamido)benzoate 
• 126674-91-7 2-(5,6-dimethoxybenzo[b]thiophene-2-carboxamido)benzoic acid 
• 1295537-09-5 2-(1,1-dioxo-5,6-dimethoxybenzo[b]thiophene-2-carboxamido)benzoic acid 
• 23046-03-9 5,6-dimethoxy-benzo[b]thiophene-2-carboxylic acid 
• 91715-47-8 5,6-dimethoxybenzo[b]thiophene 

Relevant academic research and scientific papers

BENZOTHIOPHENE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF

A compound represented by formula (I) or a pharmaceutically acceptable salt, a stereoisomer, a tautomer, a polymorph, a solvate, an N-oxide, an isotope labeled compound, a metabolite or a prodrug thereof, a pharmaceutical composition and a pill container comprising same, a preparation method therefor, and the use thereof in the preparation of drugs for preventing or treating STING-mediated related diseases.

DIMERIC COMPOUNDS AS STING AGONISTS

The present disclosure relates to dimeric STING agonists of Formulae (I), (II), (III), (IV), (V), and (VI), and pharmaceutically acceptable salts thereof. The present disclosure also relates to methods of preparing the compounds and methods of using the c

Amide compound and preparation method and application thereof

The invention relates to an amide compound and a preparation method and application thereof. Specifically, the present invention relates to a compound of formula I or a pharmaceutically acceptable salt, stereoisomer, tautomer, polymorph, solvate, N-oxide, isotope labeled compound, metabolite or prodrug thereof, pharmaceutical compositions and kits comprising the same, processes for their preparation and their use in the preparation of medicaments for the treatment of STING-mediated related diseases.

Benzothiophene amide compound and preparation method and application thereof

The invention relates to a benzothiophene amide compound and a preparation method and application thereof. Specifically, the present application relates to a compound represented by formula (I), a stereoisomer, a tautomer, a polymorph, an N-oxide, an isotope labeled compound, a metabolite or a prodrug thereof, or a solvate or a pharmaceutically acceptable salt thereof, and the compound can be usedfor preparing a drug for treating a cell proliferative disease.

BENZO[b]THIOPHENE COMPOUNDS AS STING AGONISTS

Compounds of general formula (Ia), compounds of general formula (Ia′), compounds of general formula (Ib), compounds of general formula (Ib′), compounds of general formula (I), compounds of general formula (I′), and their pharmaceutically acceptable salts,

THE 5,6-DIMETHOXY-1, 1-DIOXOBENZO(B)THIOPHENE-2-METHYLOXYCARBONYL (DM-BSMOC) AND RELATED AMINO-PROTECTING GROUPS

Amino acid protecting groups are provided for use in peptide synthesis. Particular compounds disclosed include 5,6-dimethoxy-l,l-dioxobenzo[b]thiophi methyloxycarbonyl (DM-Bsmoc) and related amino-protecting groups.

Efficient synthetic approach to substituted benzo[b]furans and benzo[b]thiophenes by iodine-promoted cyclization of enaminones

An efficient synthetic approach to the substituted benzo[b]furan and benzo[b]thiophene scaffolds by iodine-mediated cyclization of the corresponding enaminones is described. This protocol was applied to a large series of these latter precursors to afford the respective benzoheterocycles substituted at the C-2 position by a carbonyl group functionality. A study of the factors that control this process reveals that the reactivity depends on the presence of electron-donor groups in the aryl ring of the aryloxycarbonylic and arylthiocarbonylic moieties.

FUSED RING ANALOGUES OF ANTI-FIBROTIC AGENTS

The present invention relates to arylcarbonyl and heteroarylcarbonyl anthranilate compounds that may be useful as anti-fibrotic agents. The present invention also relates to methods for their preparation, pharmaceutical compositions containing these compounds and uses of these compounds in the treatment disorders.

Benzothiophene derivatives and medicinal use thereof

A benzothiophene derivative represented by formula (1): can activate a peroxisome proliferator-activated receptor (PPAR) α or γ which is an intranuclear transcription factor. The compound may be used as an active ingredient to give a drug for preventing o