35213-85-5

Usage

Uses

Used in Analytical Chemistry:
5-METHYLTETRAZOLO[1,5-A]QUINOLINE is used as a fluorescent probe for detecting metal ions, as it can form complexes with certain metals. This application is valuable in the field of analytical chemistry for the sensitive and selective detection of metal ions, which can be important for environmental monitoring and other applications.
Used in Pharmaceutical Industry:
5-METHYLTETRAZOLO[1,5-A]QUINOLINE is used as a potential drug candidate for its antimicrobial and antitumor activities. Its ability to target and inhibit the growth of harmful microorganisms and tumor cells makes it a promising compound for the development of new antibiotics and anticancer drugs.
Used in Photodynamic Therapy:
5-METHYLTETRAZOLO[1,5-A]QUINOLINE is used as a potential photosensitizer in photodynamic therapy, a treatment for cancer and other diseases. Its ability to absorb light and generate reactive oxygen species upon illumination makes it a candidate for the targeted destruction of diseased cells while minimizing damage to healthy tissues.
Used in Materials Science:
5-METHYLTETRAZOLO[1,5-A]QUINOLINE is used in the development of new materials with unique properties, such as luminescent materials for sensing applications or as components in organic light-emitting diodes (OLEDs). Its ability to form complexes with metal ions and exhibit fluorescence can be harnessed to create materials with tailored properties for specific applications.

InChI:InChI=1/C10H8N4/c1-7-6-10-11-12-13-14(10)9-5-3-2-4-8(7)9/h2-6H,1H3

Upstream product

• 21703-52-6 2-hydrazinyl-4-methylquinoline 
• 4437-65-4 4-methyl-2-thioxo-1H-quinoline 
• 634-47-9 2-chloro-4-methylquinoline 

Downstream Products

• 1224886-25-2 C₁₈H₁₈N₄ 
• 1224886-26-3 C₁₉H₁₆N₄ 
• 1224886-24-1 4-methyl-2-(4-phenyl-1H-1,2,3-triazol-1-yl)quinoline 

Relevant academic research and scientific papers

Efficient uncatalyzed conversion of primary and secondary thioamides into 1-substituted, 5-substituted, 1, 5-disubstituted and annulated tetrazoles

Unprecedented high-yield simple and mild conversion of primary aliphatic and aromatic thioamides into 5-substituted tetrazoles on treatment with a combination of tetrachlorosilane and sodium azide in refluxing acetonitrile has been achieved. Secondary acyclic, cyclic, and heterocyclic thioamides could also be transformed in high yields into 1-substituted, 1,5-disubstituted, or annulated tetrazoles under the same reaction condition. Copyright Taylor & Francis Group, LLC.

Fused tetrazoles as azide surrogates in click reaction: Efficient synthesis of N-heterocycle-substituted 1,2,3-triazoles

Figure presented It has been shown that various pyrido-, quinolino-, pyrazino-, and quinoxalinotetrazoles can be used efficiently as azide components in Cu-catalyzed click reaction with alkynes. This method allows for efficient synthesis of a wide variety

Microwave assisted synthesis and antifungal activity of 1,2,4-triazine, 1,2,4-triazole, tetrazole and pyrazole derivatives

The condensation reactions of 2-hydrazino-4-methylquinoline with diethyl oxalate, ethyl bromoacetate, aromatic aldehydes, acetic anhydride, nitrous acid and different acetophenones followed by DMF and POCl3 under microwave irradiation and by conventional methods are described. The reaction rate is enhanced tremendously under microwave irradiation as compared to conventional method with improved yields. All the newly synthesised compounds have been screened for antifungal activity against fungi A. niger andA.flavous.