352212-99-8Relevant academic research and scientific papers
Reaction of acylpyruvic acid esters with hydrazides
Pakal'Nis,Zerova,Yakimovich,Alekseyev
, p. 408 - 416 (2013/07/26)
Hydrazides reacted with acylpyruvic acid esters possessing a terminal straight chain alkyl substituent at the C=O bond distal from the ester group, giving 5-hydroxy-2-pyrazolines. Acylpyruvates with bulky terminal substituents underwent condensation at the C=O bond adjacent to the ester group, giving products with hydrazone or 5-hydroxy-2-pyrazoline structure and capable of displaying ring-chain equilibrium between these tautomers in solution.
