352275-17-3

Basic information

• Product Name: 3a,6-Epoxy-3aH-isoindole, 2-(chloroacetyl)-1,2,3,6,7,7a-hexahydro-, (3aR,6R,7aR)-rel- (9CI)
• Synonyms: 3a,6-Epoxy-3aH-isoindole, 2-(chloroacetyl)-1,2,3,6,7,7a-hexahydro-, (3aR,6R,7aR)-rel- (9CI)
• CAS NO: 352275-17-3
• Molecular Formula: C10H12ClNO2
• Molecular Weight: 213.66
• Product Categories: ACETYLHALIDE
• Mol File: 352275-17-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3a,6-Epoxy-3aH-isoindole, 2-(chloroacetyl)-1,2,3,6,7,7a-hexahydro-, (3aR,6R,7aR)-rel- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3a,6-Epoxy-3aH-isoindole, 2-(chloroacetyl)-1,2,3,6,7,7a-hexahydro-, (3aR,6R,7aR)-rel- (9CI)(352275-17-3)
• EPA Substance Registry System: 3a,6-Epoxy-3aH-isoindole, 2-(chloroacetyl)-1,2,3,6,7,7a-hexahydro-, (3aR,6R,7aR)-rel- (9CI)(352275-17-3)

Safety Data

• Hazardous Substances Data: 352275-17-3(Hazardous Substances Data)

Upstream product

• 53175-33-0 N-(2-furylmethyl)-N-(prop-2-en-1-yl)amine 
• 98-01-1 furfural 
• 60549-91-9 N-Allyl-2-chloro-N-furan-2-ylmethyl-acetamide 

Relevant articles and documents

Intramolecular diels - Alder cycloaddition of N-allyl-N-(2-furylmethyl)amides - First step of a new route towards the synthesis of a densely functionalized pyrrolizidine ring

The intramolecular Diels - Alder reaction of N-allyl-N-(2-furylmethyl)amides to exo-N-acyl-3-aza-10-oxatricyclo [5.2.1.01-5]dec-8-enes is described. The cycloaddition is controlled not only by the size of the amide appendage, but also by electronegativity of the amide. An example of a new approach towards the synthesis of a highly functionalized pyrrolizidine ring, which links this Diels - Alder cycloaddition to an halogen atom transfer radical cyclization, is reported.