Cas 352281-83-5,(R)-2-{(2E,7E)-(5S,6R)-5-[2-(3-tert-Butoxycarbonylamino-propionyloxy)-2-methyl-propionyloxy]-6-methyl-8-phenyl-octa-2,7-dienoylamino}-3-(4-methoxy-phenyl)-propionic acid 2-trimethylsilanyl-ethyl ester

352281-83-5

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Basic information

Product Name: (R)-2-{(2E,7E)-(5S,6R)-5-[2-(3-tert-Butoxycarbonylamino-propionyloxy)-2-methyl-propionyloxy]-6-methyl-8-phenyl-octa-2,7-dienoylamino}-3-(4-methoxy-phenyl)-propionic acid 2-trimethylsilanyl-ethyl ester
Synonyms:
CAS NO:352281-83-5
Molecular Formula:
Molecular Weight: 781.031
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (R)-2-{(2E,7E)-(5S,6R)-5-[2-(3-tert-Butoxycarbonylamino-propionyloxy)-2-methyl-propionyloxy]-6-methyl-8-phenyl-octa-2,7-dienoylamino}-3-(4-methoxy-phenyl)-propionic acid 2-trimethylsilanyl-ethyl ester(CAS DataBase Reference)
NIST Chemistry Reference: (R)-2-{(2E,7E)-(5S,6R)-5-[2-(3-tert-Butoxycarbonylamino-propionyloxy)-2-methyl-propionyloxy]-6-methyl-8-phenyl-octa-2,7-dienoylamino}-3-(4-methoxy-phenyl)-propionic acid 2-trimethylsilanyl-ethyl ester(352281-83-5)
EPA Substance Registry System: (R)-2-{(2E,7E)-(5S,6R)-5-[2-(3-tert-Butoxycarbonylamino-propionyloxy)-2-methyl-propionyloxy]-6-methyl-8-phenyl-octa-2,7-dienoylamino}-3-(4-methoxy-phenyl)-propionic acid 2-trimethylsilanyl-ethyl ester(352281-83-5)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 352281-83-5(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 352281-83-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,2,2,8 and 1 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 352281-83:
(8*3)+(7*5)+(6*2)+(5*2)+(4*8)+(3*1)+(2*8)+(1*3)=135
135 % 10 = 5
So 352281-83-5 is a valid CAS Registry Number.

352281-83-5Upstream product

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352281-83-5Relevant academic research and scientific papers

Synthesis of stable analogs in blood and conformational analysis of arenastatin A, a potent cytotoxic spongean depsipeptide

Murakami, Nobutoshi,Tamura, Satoru,Wang, Weiqi,Takagi, Tatsuya,Kobayashi, Motomasa

, p. 4323 - 4336 (2007/10/03)

In order to produce stable analogs in blood of arenastatin A, a potent cytotoxic depsipeptide from the marine sponge Dysidea arenaria, we synthesized four analogs in which the 15-20 ester linkage was modified. Among them, the carba analog and 20-deoxo analog showed stability in serum. The conformation of arenastatin A and its three analogs were analyzed by distance-restrained molecular dynamic calculation to elucidate a three-dimensional stereostructure contributing to the extremely potent cytotoxicity of arenastatin A.

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