352305-48-7

Upstream product

• 208722-53-6 7-iodoimidazo[5,1-b]-thiazole 
• 352305-49-8 1-iodo-3-(4-nitrobenzyloxycarbonyl)aminopropane 

Downstream Products

• 352305-47-6 7-[3-(4-Nitrobenzyloxycarbonyl)-aminopropyl]thio-2-(tri-n-butylstannyl)imidazo[5,1-b]-thiazole 

Relevant academic research and scientific papers

Novel carbapenem derivatives of quarternary salt type

An objective of the present invention is to provide carbapenem derivatives which have potent antibiotic activity against MRSA, PRSP, Influenzavirus, and β-lactamase-producing bacteria and are stable against DHP-1. The compounds according to the present invention are compounds represented by formula (I) or pharmaceutically acceptable salts thereof: wherein R1 represents H or methyl; R2 and R3 each independently represent H, halogen, lower alkyl or the like; R4 represents optionally substituted lower alkylthio or the like; and R5 represents optionally substituted lower alkyl or the like.

Novel carbapenum derivatives

An objective of the present invention is to provide carbapenem derivatives which have potent antibiotic activity against MRSA, PRSP, Influenzavirus, and β-lactamase-producing bacteria and are stable against DHP-1. The compounds according to the present invention are compounds represented by formula (I) or pharmaceutically acceptable salts thereof: wherein R1 represents H or methyl; R2 and R3 represent H, a halogen atom, alkyl or the like; and R4 represents substituted lower alkylthio or the like.