35231-36-8

Usage

InChI:InChI=1/C14H23NO2.ClH/c1-10(2)12-9-13(16)11(3)8-14(12)17-7-6-15(4)5;/h8-10,16H,6-7H2,1-5H3;1H

Upstream product

• 54-32-0 thymoxamine 

Downstream Products

• 112865-55-1 [2-(2-isopropyl-5-methyl-4-propoxy-phenoxy)-ethyl]-dimethyl-propyl-ammonium; bromide 
• 46890-46-4 [2-(2-isopropyl-4-methoxy-5-methyl-phenoxy)-ethyl]-dimethyl-amine 

Relevant academic research and scientific papers

Nitrosated and nitrosylated alpha-adrenergic receptor antagonists, compositions and methods of use

The present invention describes novel nitrosated and/or nitrosylated α-adrenergic receptor antagonists, and novel compositions containing at least one nitrosated and/or nitrosylated α-adrenergic receptor antagonist, and, optionally, one or more compounds

Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses

Disclosed are nitrosated and nitrosylated α-adrenergic receptor antagonists, compositions of an α-adrenergic receptor antagonist (α-antagonist), which can optionally be substituted with at least one NO or NO2 moiety, and a compound that donates

Process for the preparation of 4-[2-(dimethylamino)-ethoxy]2-methyl-5-(1-methylethyl)-phenol esters and their salts

This invention relates to a process for the preparation of 4-[2-(dimethylamino)-ethoxy]-2-methyl-5-(1-methylethyl)-phenol esters (I) and their salts with organic and inorganic acids comprising the reaction of thymol with a salt of an 1-halo-dimethylaminoethane to obtain ethylamine-N,N-dimethyl-2-(thymyloxy) (II), the subsequent reaction of (II) with an acylating agent according to the Friedel and Kraft reaction to obtain 4-[2-(dimethylamino)-ethoxy]-2-methyl-5-(1-methylethyl)-1-acyl-benzene (III) and the oxidation of (III) to obtain the products (I) which, if desired, may be transformed in their salts with organic or inorganic acids. This process allows to obtain the products (I) in high quality and quantity without isolating any intermediate product.