352331-99-8

Basic information

• Product Name: N-(2-bromo-4-methylphenyl)-3-phenylpropanamide
• Synonyms: benzenepropanamide, N-(2-bromo-4-methylphenyl)-; N-(2-Bromo-4-methylphenyl)-3-phenylpropanamide
• CAS NO: 352331-99-8
• Molecular Formula: C₁₆H₁₆BrNO
• Molecular Weight: 318.2083
• Mol File: 352331-99-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 472.3°C at 760 mmHg
• Flash Point: 239.5°C
• Density: 1.37g/cm³
• Vapor Pressure: 4.32E-09mmHg at 25°C
• Refractive Index: 1.625
• CAS DataBase Reference: N-(2-bromo-4-methylphenyl)-3-phenylpropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-bromo-4-methylphenyl)-3-phenylpropanamide(352331-99-8)
• EPA Substance Registry System: N-(2-bromo-4-methylphenyl)-3-phenylpropanamide(352331-99-8)

Safety Data

• Hazardous Substances Data: 352331-99-8(Hazardous Substances Data)

Upstream product

• 583-68-6 2-bromo-p-toluidine 
• 645-45-4 hydrocinnamic acid chloride 

Relevant articles and documents

Palladium-catalyzed anilide ortho-arylation and subsequent one-pot cyclization to phenanthridines

(Chemical Equation Presented) The palladium-catalyzed direct arylation of anilides possessing several N-acyl substituents has been demonstrated. Removal of the acyl group by base hydrolysis allows a short and efficient synthesis of 2-aryl or 2,6-diarylanilines. The method is functional group tolerant and allows the presence of chloride and bromide substituents on both the anilide and aryl iodide coupling components. The arylation products can be converted to phenanthridines by the reaction with trifluoroacetic anhydride.