352349-19-0Relevant academic research and scientific papers
Acid-base properties of 1,2,5-oxadiazoles. III. Furazanylacetic acids
Tselinskii,Mel'nikova,Zelenov
, p. 734 - 737 (2007/10/03)
Synthesis of 5 representatives of 4-R-furazan-3-acetic acids (R = H, CH3, NH2, NO2, N3) and 4,4′-azo- and 4,4′-azoxyfurazan-3-acetic acids is described. The pKa constants of some 4-R-furazan-3-acetic acids are determined using potentiometric titration, and inductive Taft constants of 4-substituted furanazyl groups are evaluated. The furazan ring is shown to possess a weak negative inductive effect and low conduction of polar effect of a substituent.
