3524-05-8

Upstream product

• 20615-75-2 4-azido-3-nitro-toluene 

Downstream Products

• 20304-86-3 5-methyl-benzo[1,2,5]oxadiazole 
• 1451060-21-1 2-cyano-3-(cyclohexanecarboxamido)-7-methylquinoxaline 1,4-dioxide 
• 1426916-64-4 7-methyl-3-(3-chlorophenyl)quinoxaline-2-carbonitrile-1,4-dioxide 
• 1426916-78-0 7-methyl-3-(4-nitrophenyl)quinoxaline-2-carbonitrile-1,4-dioxide 
• 1426916-76-8 7-methyl-3-(4-bromophenyl)quinoxaline-2-carbonitrile-1,4-dioxide 
• 1426916-74-6 7-methyl-3-(3-methylphenyl)quinoxaline-2-carbonitrile-1,4-dioxide 
• 1421426-48-3 2-cyano-3-(4-(4-fluorophenyl)piperazine-1-carboxamido)-7-methylquinoxaline 1,4-dioxide 
• 1421426-45-0 2-cyano-7-methyl-3-(4-(4-(trifluoromethyl)phenyl)piperazine-1-carboxamido)quinoxaline 1,4-dioxide 
• 1421426-41-6 2-cyano-7-methyl-3-(4-(2-nitro-4-(trifluoromethyl)phenyl)piperazine-1-carboxamido)quinoxaline 1,4-dioxide 
• 1421426-51-8 2-cyano-3-(4-(4-methoxyphenyl)piperazine-1-carboxamido)-7-methylquinoxaline 1,4-dioxide 
• 1323954-28-4 3-(2-acetoxybenzamido)-2-cyano-7-methylquinoxaline 1,4-dioxide 
• 1004981-18-3 C₁₈H₁₆N₂O₄ 
• 1297593-70-4 C₁₈H₁₆N₂O₄ 
• 1079038-64-4 7-methyl-(3-(4'-fluoro)phenyl)quinoxaline-2-carbonitrile 1,4-di-N-oxide 

Relevant academic research and scientific papers

1,2,3-Triazolo[1,5-a]quinoxalines: Synthesis and binding to benzodiazepine and adenosine receptors

This paper reports the synthesis and binding assays toward benzodiazepine and adenosine A1 and A(2A) receptors of new 1,2,3-triazolo[1,5-a]quinoxalin-4-one derivatives. The prepared compounds show good affinity toward the benzodiazepine receptor (K(i) 53-314 nM); the GABA ratio values suggest an inverse agonist activity for the N(5) unsubstituted compounds 6b-d and an agonist activity for the N(5) methylated compounds 7a-c. Some derivatives of both series show good affinity (K(i) 1 receptorial subtype.