3524-05-8

Basic information

• Product Name: 6-methyl-2,1,3-benzoxadiazole 1-oxide
• Synonyms: 2,1,3-Benzoxadiazole, 6-methyl-, 1-oxide; 6-Methyl-2,1,3-benzoxadiazole 1-oxide; 6-Methylbenzofurazan-1-oxide
• CAS NO: 3524-05-8
• Molecular Formula: C₇H₆N₂O₂
• Molecular Weight: 150.1347
• Mol File: 3524-05-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 263.6°C at 760 mmHg
• Flash Point: 113.2°C
• Density: 1.4g/cm³
• Vapor Pressure: 0.0167mmHg at 25°C
• Refractive Index: 1.648
• CAS DataBase Reference: 6-methyl-2,1,3-benzoxadiazole 1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methyl-2,1,3-benzoxadiazole 1-oxide(3524-05-8)
• EPA Substance Registry System: 6-methyl-2,1,3-benzoxadiazole 1-oxide(3524-05-8)

Safety Data

• Hazardous Substances Data: 3524-05-8(Hazardous Substances Data)

Upstream product

• 20615-75-2 4-azido-3-nitro-toluene 

Downstream Products

• 98501-49-6 2-(4-Methoxy-phenyl)-5-methyl-3-oxy-benzoimidazol-1-ol 
• 98501-47-4 5-Methyl-3-oxy-2-phenyl-benzoimidazol-1-ol 
• 1228550-61-5 3,7-dimethyl-1,4-di-N-oxidequinoxaline-2-carboxylic acid 2-benzylamide 
• 1228550-70-6 3,7-dimethyl-1,4-di-N-oxidequinoxaline-2-carboxylic acid 2-(4-methoxybenzyl)-amide 
• 1228550-78-4 3,7-dimethyl-1,4-di-N-oxidequinoxaline-2-carboxylic acid 2-phenylethylamide 
• 1253059-02-7 3,7-dimethylquinoxaline-2-carboxylic acid p-bromobenzylamide 1,4-di-N-oxide 
• 1253059-06-1 3,7-dimethylquinoxaline-2-carboxylic acid p-methylbenzylamide 1,4-di-N-oxide 
• 1253058-93-3 3,7-dimethylquinoxaline-2-carboxylic acid (p-trifluoromethyl)benzylamide 1,4-di-N-oxide 
• 1421426-51-8 2-cyano-3-(4-(4-methoxyphenyl)piperazine-1-carboxamido)-7-methylquinoxaline 1,4-dioxide 
• 1421426-41-6 2-cyano-7-methyl-3-(4-(2-nitro-4-(trifluoromethyl)phenyl)piperazine-1-carboxamido)quinoxaline 1,4-dioxide 
• 1421426-45-0 2-cyano-7-methyl-3-(4-(4-(trifluoromethyl)phenyl)piperazine-1-carboxamido)quinoxaline 1,4-dioxide 
• 1421426-48-3 2-cyano-3-(4-(4-fluorophenyl)piperazine-1-carboxamido)-7-methylquinoxaline 1,4-dioxide 
• 1451060-21-1 2-cyano-3-(cyclohexanecarboxamido)-7-methylquinoxaline 1,4-dioxide 

Relevant articles and documents

1,2,3-Triazolo[1,5-a]quinoxalines: Synthesis and binding to benzodiazepine and adenosine receptors

This paper reports the synthesis and binding assays toward benzodiazepine and adenosine A1 and A(2A) receptors of new 1,2,3-triazolo[1,5-a]quinoxalin-4-one derivatives. The prepared compounds show good affinity toward the benzodiazepine receptor (K(i) 53-314 nM); the GABA ratio values suggest an inverse agonist activity for the N(5) unsubstituted compounds 6b-d and an agonist activity for the N(5) methylated compounds 7a-c. Some derivatives of both series show good affinity (K(i) 1 receptorial subtype.