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2-Isobutyl-5-methyl-2H-pyrazol-3-ylamine is an organic compound with the chemical formula C8H16N2. It is a derivative of pyrazole, a heterocyclic compound consisting of a five-membered aromatic ring with two nitrogen atoms. This specific compound features an isobutyl group (a branched chain of three carbon atoms) at the 2-position and a methyl group (one carbon atom) at the 5-position. The amine group (-NH2) is attached to the 3-position of the pyrazole ring. 2-ISOBUTYL-5-METHYL-2H-PYRAZOL-3-YLAMINE is known for its potential applications in the synthesis of various pharmaceuticals and agrochemicals, as well as its use as an intermediate in the production of certain chemicals. Its properties, such as solubility and reactivity, can be influenced by the presence of the isobutyl and methyl groups, making it a versatile building block in organic chemistry.

3524-36-5

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3524-36-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 3524-36-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,5,2 and 4 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 3524-36:
(6*3)+(5*5)+(4*2)+(3*4)+(2*3)+(1*6)=75
75 % 10 = 5
So 3524-36-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H15N3/c1-6(2)5-11-8(9)4-7(3)10-11/h4,6H,5,9H2,1-3H3

3524-36-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-methyl-2-(2-methylpropyl)pyrazol-3-amine

1.2 Other means of identification

Product number -
Other names 1-ISOBUTYL-3-METHYL-1H-PYRAZOL-5-AMINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3524-36-5 SDS

3524-36-5Downstream Products

3524-36-5Relevant academic research and scientific papers

Discovery and Characterization of 1H-Pyrazol-5-yl-2-phenylacetamides as Novel, Non-Urea-Containing GIRK1/2 Potassium Channel Activators

Wieting, Joshua M.,Vadukoot, Anish K.,Sharma, Swagat,Abney, Kristopher K.,Bridges, Thomas M.,Daniels, J. Scott,Morrison, Ryan D.,Wickman, Kevin,Weaver, C. David,Hopkins, Corey R.

, p. 1873 - 1879 (2017/09/25)

The G protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) are a family of inward-rectifying potassium channels, and there is significant evidence supporting the roles of GIRKs in a number of physiological processes and as potential targets for numerous indications. Previously reported urea containing molecules as GIRK1/2 preferring activators have had significant pharmacokinetic (PK) liabilities. Here we report a novel series of 1H-pyrazolo-5-yl-2-phenylacetamides in an effort to improve upon the PK properties. This series of compounds display nanomolar potency as GIRK1/2 activators with improved brain distribution (rodent Kp > 0.6).

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