3524-40-1 Usage
Uses
Used in Organic Chemistry:
2-(2-CHLORO-BENZYL)-5-METHYL-2H-PYRAZOL-3-YLAMINE is used as a chemical intermediate for the synthesis of various organic compounds. Its unique structure, which includes a benzylamine moiety and a pyrazole ring, makes it a potentially valuable building block in the development of new molecules with specific properties.
Used in Medicinal Chemistry:
2-(2-CHLORO-BENZYL)-5-METHYL-2H-PYRAZOL-3-YLAMINE is used as a potential lead compound in the discovery and development of new pharmaceuticals. Its structural features may contribute to its interaction with biological targets, such as enzymes or receptors, which could lead to the identification of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 3524-40-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,5,2 and 4 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 3524-40:
(6*3)+(5*5)+(4*2)+(3*4)+(2*4)+(1*0)=71
71 % 10 = 1
So 3524-40-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H12ClN3/c1-8-6-11(13)15(14-8)7-9-4-2-3-5-10(9)12/h2-6H,7,13H2,1H3
3524-40-1Relevant academic research and scientific papers
HSP90 INHIBITORS AND USES THEREOF
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Paragraph 00181; 00196; 00211, (2020/11/23)
Herein is described the design and synthesis of resorcylate aminopyrazole compounds. These compounds show broad, potent and fungal-selective Hsp90 inhibitory activity. These compounds also find use in treating Hsp90 related deseases.
Design and Synthesis of Fungal-Selective Resorcylate Aminopyrazole Hsp90 Inhibitors
Huang, David S.,Leblanc, Emmanuelle V.,Shekhar-Guturja, Tanvi,Robbins, Nicole,Krysan, Damian J.,Pizarro, Juan,Whitesell, Luke,Cowen, Leah E.,Brown, Lauren E.
, p. 2139 - 2180 (2019/10/11)
The molecular chaperone Hsp90, essential in all eukaryotes, plays a multifaceted role in promoting survival, virulence, and drug resistance across diverse pathogenic fungal species. The chaperone is also critically important, however, to the pathogen's hu
