3524-41-2 Usage
Pyrazole derivative
A compound derived from the pyrazole ring structure This indicates that the compound is based on the pyrazole ring system, which is a five-membered heterocyclic ring containing two nitrogen atoms.
Chlorine-substituted benzyl group
A benzyl group (a phenyl group attached to a methyl group) with a chlorine atom attached This describes the presence of a chlorine atom on the benzyl group, which may influence the compound's reactivity and properties.
Methyl group attached to the pyrazole ring
A methyl (CH3) group directly connected to the pyrazole ring This suggests that the compound has a methyl substituent on the pyrazole ring, which can affect its chemical and biological activities.
Building block in synthesis
Commonly used as a starting material in the preparation of pharmaceuticals and agrochemicals This highlights the compound's utility in the synthesis of various chemical products, particularly in the fields of medicine and agriculture.
Potential anti-inflammatory and anti-cancer properties
Has been studied for its possible effects on reducing inflammation and inhibiting cancer cell growth This indicates that the compound may have therapeutic applications in the treatment of inflammatory conditions and cancer.
Drug development
Involved in the development of new drugs targeting various diseases This suggests that the compound may be useful in the creation of novel pharmaceuticals for a range of medical conditions.
Industrial and research applications
May have other uses in industry and scientific research due to its chemical properties and potential biological activities This implies that the compound could have a wide range of applications beyond its use in pharmaceuticals and agrochemicals, thanks to its unique characteristics.
Check Digit Verification of cas no
The CAS Registry Mumber 3524-41-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,5,2 and 4 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3524-41:
(6*3)+(5*5)+(4*2)+(3*4)+(2*4)+(1*1)=72
72 % 10 = 2
So 3524-41-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H12ClN3/c1-8-6-11(13)15(14-8)7-9-2-4-10(12)5-3-9/h2-6H,7,13H2,1H3
3524-41-2Relevant academic research and scientific papers
Design, synthesis and biological evaluation of spiropyrazolopyridone derivatives as potent dengue virus inhibitors
Chen, Haiying,Shi, Pei-Yong,Xie, Xuping,Xu, Jimin,Xue, Yu,Ye, Na,Zhou, Jia,Zou, Jing
, (2020/04/10)
The effective treatment for dengue virus infection continues to be a challenge. We herein reported our continued SAR exploration on the spiropyrazolopyridone scaffold. Introducing different substituents at the 3?- or 5?-site of the pyrazolopyridone core or moving the benzyl chain to the adjacent nitrogen led to a significant loss of potency on DENV-2. While a narrow range of substitutions were tolerated at the para-position of the phenyl ring, di-substitution on the phenyl ring is beneficial for DENV-2 potency and has variable influences on DENV-3 potency depending on the exact compound. Among these molecules, compounds 22 (JMX0376) with 4-chloro-3-fluorobenzyl and 24 (JMX0395) with 2,4-bis(trifluoromethyl)benzyl showed the most potent and broadest inhibitory activities against DENV-1 to ?3 with nanomolar to low micromolar EC50 values.
