3524-49-0

Usage

Uses

Used in Organic Synthesis:
1H-Pyrazol-5-amine,1,4-dimethyl-(9CI) is utilized as a building block in organic synthesis for the creation of various chemical compounds. Its unique structure allows for the development of new molecules with specific properties, making it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Research Applications:
In the field of research, 1H-Pyrazol-5-amine,1,4-dimethyl-(9CI) serves as a key compound for studying the properties and reactions of pyrazole derivatives. It can be used to investigate the reactivity of the pyrazole ring and its substituents, as well as to explore the potential of 1H-Pyrazol-5-amine,1,4-dimethyl-(9CI) in various chemical reactions and processes.
Used in Pharmaceutical Development:
1H-Pyrazol-5-amine,1,4-dimethyl-(9CI) may have potential uses in the development of new pharmaceuticals. Its unique structure and reactivity can be leveraged to design and synthesize novel drug candidates with specific therapeutic properties. 1H-Pyrazol-5-amine,1,4-dimethyl-(9CI) can be further modified and optimized to enhance its pharmacological activity and selectivity, contributing to the discovery of new treatments for various diseases.
Used in Material Science:
1H-Pyrazol-5-amine,1,4-dimethyl-(9CI) may also have potential applications in the development of new materials and chemical processes. Its unique chemical properties can be harnessed to create innovative materials with specific characteristics, such as improved stability, reactivity, or selectivity. This can lead to advancements in various industries, including chemical manufacturing, energy production, and environmental protection.

InChI:InChI=1/C5H9N3/c1-4-3-7-8(2)5(4)6/h3H,6H2,1-2H3

Upstream product

• 31037-02-2 ethyl 5-amino-1-methyl-1H-pyrazole-4-carboxylate 
• 28786-90-5 2,3-dibromo-2-methylpropanenitrile 
• 60-34-4 methylhydrazine 

Downstream Products

• 1453849-93-8 (S)-1-(1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1,4-dimethyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one 

Relevant academic research and scientific papers

Heterocyclic acylamide derivative and preparation method and pharmaceutical application thereof

The invention relates to a heterocyclic acylamide derivative and a preparation method and pharmaceutical application thereof, in particular to a heterocyclic acylamide derivative shown as a general formula (I) or a stereoisomer and a pharmaceutically-acce

Tuning azoheteroarene photoswitch performance through heteroaryl design

Photoswitchable compounds, which can be reversibly switched between two isomers by light, continue to attract significant attention for a wide array of applications. Azoheteroarenes represent a relatively new but understudied type of photoswitch, where one of the aryl rings from the conventional azobenzene class has been replaced with a fivemembered heteroaromatic ring. Initial studies have suggested the azoheteroarenes-the arylazopyrazoles in particular- to have excellent photoswitching properties (quantitative switching and long Z isomer half-life). Here we present a systematic computational and experimental study to elucidate the origin of the long thermal half-lives and excellent addressability of the arylazopyrazoles, and apply this understanding to determine important structure-property relationships for a wide array of comparable azoheteroaryl photoswitches. We identify compounds with Z isomer half-lives ranging from seconds to hours, to days and to years, and variable absorption characteristics, all through tuning of the heteraromatic ring. Conformation perhaps plays the largest role in determining such properties: the compounds with the longest isomerization half-lives adopt a T-shaped ground state Z isomer conformation and proceed through a T-shaped isomerization pathway, whereas the most complete photoswitching is achieved for compounds that have a twisted (rather than T-shaped) Z isomer conformation. By balancing these factors, we report a new azopyrazole 3pzH, which can be quantitatively switched to its Z isomer (1/2 = 74 d at 25 °C). Given the large tunability of their properties, the predictive nature of their performance, and the other functional opportunities afforded by usage of a heteroaromatic system, we believe the azoheteroaryl photoswitches to have huge potential in a wide range of optically addressable applications.

Aminopyrazoles. IV. Pyrazol-3- and 5-amines from 2,3-dihaloalkanenitriles or 3-Chloroacrylonitriles and Hydrazines

2,3-Dihalopropanenitriles and substituted 3-chloropropenenitriles react with hydrazines in basic solution to form either pyrazol-3-amines 4 or pyrazol-5-amines 5 or a mixture of both isomers.